SEW84
TL;DR: SEW84 (CAS 259089-67-3) is a chemical compound with molecular formula C19H14F4N4OS and molecular weight 422.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[[1-(4-fluorophenyl)pyrrole-2-carbonyl]amino]-3-[3-(trifluoromethyl)phenyl]thiourea
Also Known As: SEW84, 147B3, J3.776.309H, 1-[[1-(4-fluorophenyl)pyrrole-2-carbonyl]amino]-3-[3-(trifluoromethyl)phenyl]thiourea, 1-(4-fluorophenyl)-N-({[3-(trifluoromethyl)phenyl]carbamothioyl}amino)pyrrole-2-carboxamide
| Molecular Formula | C19H14F4N4OS |
|---|---|
| Molecular Weight | 422.08 g/mol |
| LogP | 4.2666 |
| Topological Polar Surface Area | 58.09 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 422.08246 |
| Heavy Atoms | 29 |
| Complexity | 1031.1885 |
Chemical Identifiers
| CAS Number | 259089-67-3 |
|---|---|
| SMILES | C1=CC(=CC(=C1)NC(=S)NNC(=O)C2=CC=CN2C3=CC=C(C=C3)F)C(F)(F)F |
Product Overview
SEW84 (CAS 259089-67-3), with molecular formula C19H14F4N4OS and molecular weight 422.08 g/mol. IUPAC: 1-[[1-(4-fluorophenyl)pyrrole-2-carbonyl]amino]-3-[3-(trifluoromethyl)phenyl]thiourea.
Chemical Property Profile of SEW84
Property Insights of SEW84
The XLogP value of 4.2666 indicates that SEW84 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 58.09 Ų, SEW84 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, SEW84 has 3 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of SEW84?
The CAS number of SEW84 is 259089-67-3.
What is the molecular formula of SEW84?
The molecular formula of SEW84 is C19H14F4N4OS.
What is the molecular weight of SEW84?
The molecular weight of SEW84 is 422.08 g/mol.
Where can I buy SEW84?
You can request a quote for SEW84 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for SEW84?
Yes, KEHONG BIO provides custom synthesis services for SEW84 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.