(E)-beta-Chloro-4'-fluoroacrylophenone structure

(E)-beta-Chloro-4'-fluoroacrylophenone

TL;DR: (E)-beta-Chloro-4'-fluoroacrylophenone (CAS 25871-99-2) is a chemical compound with molecular formula C9H6ClFO and molecular weight 184.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

3-chloro-1-(4-fluorophenyl)prop-2-en-1-one

Also Known As: (E)-beta-Chloro-4'-fluoroacrylophenone

CAS: 25871-99-2
Molecular Formula C9H6ClFO
Molecular Weight 184.01 g/mol
LogP 2.6
Topological Polar Surface Area 17.1 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 2
Rotatable Bonds 2
Exact Mass 184.00912
Heavy Atoms 12
Complexity 183.0

Chemical Identifiers

CAS Number 25871-99-2
SMILES C1=CC(=CC=C1C(=O)C=CCl)F
InChIKey HWXNHESDWWDHHS-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (6 patents) Specialty Chemicals (3 patents)

Product Overview

(E)-beta-Chloro-4'-fluoroacrylophenone (CAS 25871-99-2), with molecular formula C9H6ClFO and molecular weight 184.01 g/mol. IUPAC: 3-chloro-1-(4-fluorophenyl)prop-2-en-1-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of (E)-beta-Chloro-4'-fluoroacrylophenone

XLogP
2.6
TPSA (Topological Polar Surface Area)
17.1
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
2
Rotatable Bonds
2
Heavy Atoms
12
Complexity
183.0
Exact Mass
184.00912
Monoisotopic Mass
184.00912
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of (E)-beta-Chloro-4'-fluoroacrylophenone

The XLogP value of 2.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (E)-beta-Chloro-4'-fluoroacrylophenone. With a topological polar surface area (TPSA) of 17.1 Ų, (E)-beta-Chloro-4'-fluoroacrylophenone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-beta-Chloro-4'-fluoroacrylophenone has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of (E)-beta-Chloro-4'-fluoroacrylophenone?

The CAS number of (E)-beta-Chloro-4'-fluoroacrylophenone is 25871-99-2.

What is the molecular formula of (E)-beta-Chloro-4'-fluoroacrylophenone?

The molecular formula of (E)-beta-Chloro-4'-fluoroacrylophenone is C9H6ClFO.

What is the molecular weight of (E)-beta-Chloro-4'-fluoroacrylophenone?

The molecular weight of (E)-beta-Chloro-4'-fluoroacrylophenone is 184.01 g/mol.

Where can I buy (E)-beta-Chloro-4'-fluoroacrylophenone?

You can request a quote for (E)-beta-Chloro-4'-fluoroacrylophenone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for (E)-beta-Chloro-4'-fluoroacrylophenone?

Yes, KEHONG BIO provides custom synthesis services for (E)-beta-Chloro-4'-fluoroacrylophenone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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