4-methylene-3-phenyl-3,4-dihydroquinazolin-2(1H)-one
TL;DR: 4-methylene-3-phenyl-3,4-dihydroquinazolin-2(1H)-one (CAS 25809-80-7) is a chemical compound with molecular formula C15H12N2O and molecular weight 236.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-methylidene-3-phenyl-1H-quinazolin-2-one
Also Known As: 4-methylidene-3-phenyl-1H-quinazolin-2-one, 4-methylene-3-phenyl-3,4-dihydroquinazolin-2(1H)-one, J2.835.222K, 4-methylene-3-phenyl-1,3-dihydroquinazolin-2-one, 4-methylene-3-phenyl-3,4-dihydro-2(1H)-quinazolinone
| Molecular Formula | C15H12N2O |
|---|---|
| Molecular Weight | 236.09 g/mol |
| LogP | 3.7094 |
| Topological Polar Surface Area | 32.34 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 236.09496 |
| Heavy Atoms | 18 |
| Complexity | 619.4006 |
Chemical Identifiers
| CAS Number | 25809-80-7 |
|---|---|
| SMILES | C=C1C2=CC=CC=C2NC(=O)N1C3=CC=CC=C3 |
Product Overview
4-methylene-3-phenyl-3,4-dihydroquinazolin-2(1H)-one (CAS 25809-80-7), with molecular formula C15H12N2O and molecular weight 236.09 g/mol. IUPAC: 4-methylidene-3-phenyl-1H-quinazolin-2-one.
Chemical Property Profile of 4-methylene-3-phenyl-3,4-dihydroquinazolin-2(1H)-one
Property Insights of 4-methylene-3-phenyl-3,4-dihydroquinazolin-2(1H)-one
The XLogP value of 3.7094 indicates that 4-methylene-3-phenyl-3,4-dihydroquinazolin-2(1H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 32.34 Ų, 4-methylene-3-phenyl-3,4-dihydroquinazolin-2(1H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-methylene-3-phenyl-3,4-dihydroquinazolin-2(1H)-one has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-methylene-3-phenyl-3,4-dihydroquinazolin-2(1H)-one?
The CAS number of 4-methylene-3-phenyl-3,4-dihydroquinazolin-2(1H)-one is 25809-80-7.
What is the molecular formula of 4-methylene-3-phenyl-3,4-dihydroquinazolin-2(1H)-one?
The molecular formula of 4-methylene-3-phenyl-3,4-dihydroquinazolin-2(1H)-one is C15H12N2O.
What is the molecular weight of 4-methylene-3-phenyl-3,4-dihydroquinazolin-2(1H)-one?
The molecular weight of 4-methylene-3-phenyl-3,4-dihydroquinazolin-2(1H)-one is 236.09 g/mol.
Where can I buy 4-methylene-3-phenyl-3,4-dihydroquinazolin-2(1H)-one?
You can request a quote for 4-methylene-3-phenyl-3,4-dihydroquinazolin-2(1H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-methylene-3-phenyl-3,4-dihydroquinazolin-2(1H)-one?
Yes, KEHONG BIO provides custom synthesis services for 4-methylene-3-phenyl-3,4-dihydroquinazolin-2(1H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.