Duometacin structure

Duometacin

TL;DR: Duometacin (CAS 25771-23-7) is a chemical compound with molecular formula C20H19NO5 and molecular weight 353.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-[6-methoxy-3-(4-methoxybenzoyl)-2-methylindol-1-yl]acetic acid

Also Known As: Duometacin, Duometacina, Duometacine, Duometacinum, Duometacin [INN:DCF]

CAS: 25771-23-7
Molecular Formula C20H19NO5
Molecular Weight 353.13 g/mol
LogP 3.4
Topological Polar Surface Area 77.8 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 5
Rotatable Bonds 6
Exact Mass 353.1263
Heavy Atoms 26
Complexity 516.0

Chemical Identifiers

CAS Number 25771-23-7
SMILES CC1=C(C2=C(N1CC(=O)O)C=C(C=C2)OC)C(=O)C3=CC=C(C=C3)OC
InChIKey NWNBRKHCXIQLDT-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 5 IPC patent classification(s) across the SureChEMBL global patent database.

Catalysts (1 patents) Heterocyclic Building Blocks (2 patents) Organic Building Blocks (11 patents) Pharmaceutical Intermediates (14 patents) Specialty Chemicals (6 patents)

Product Overview

Duometacin (CAS 25771-23-7), with molecular formula C20H19NO5 and molecular weight 353.13 g/mol. IUPAC: 2-[6-methoxy-3-(4-methoxybenzoyl)-2-methylindol-1-yl]acetic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Duometacin

XLogP
3.4
TPSA (Topological Polar Surface Area)
77.8
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
5
Rotatable Bonds
6
Heavy Atoms
26
Complexity
516.0
Exact Mass
353.1263
Monoisotopic Mass
353.1263
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Duometacin

The XLogP value of 3.4 indicates that Duometacin is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 77.8 Ų falls within the moderate polarity range, balancing permeability and solubility for Duometacin. Following Lipinski's Rule of Five, Duometacin has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Duometacin?

The CAS number of Duometacin is 25771-23-7.

What is the molecular formula of Duometacin?

The molecular formula of Duometacin is C20H19NO5.

What is the molecular weight of Duometacin?

The molecular weight of Duometacin is 353.13 g/mol.

Where can I buy Duometacin?

You can request a quote for Duometacin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Duometacin?

Yes, KEHONG BIO provides custom synthesis services for Duometacin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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