5-(4-hydroxy-3-methoxybenzylidene)-3-(4-hydroxyphenyl)-1,3-thiazolidine-2,4-dione
TL;DR: 5-(4-hydroxy-3-methoxybenzylidene)-3-(4-hydroxyphenyl)-1,3-thiazolidine-2,4-dione (CAS 25745-34-0) is a chemical compound with molecular formula C17H13NO5S and molecular weight 343.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5Z)-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-3-(4-hydroxyphenyl)-1,3-thiazolidine-2,4-dione
Also Known As: 5-(4-hydroxy-3-methoxybenzylidene)-3-(4-hydroxyphenyl)-1,3-thiazolidine-2,4-dione, AF-399/12152023, (5Z)-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-3-(4-hydroxyphenyl)-1,3-thiazolidine-2,4-dione, (Z)-5-(4-hydroxy-3-methoxybenzylidene)-3-(4-hydroxyphenyl)thiazolidine-2,4-dione, (5Z)-5-(4-hydroxy-3-methoxybenzylidene)-3-(4-hydroxyphenyl)-1,3-thiazolidine-2,4-dione
| Molecular Formula | C17H13NO5S |
|---|---|
| Molecular Weight | 343.05 g/mol |
| LogP | 3.3473 |
| Topological Polar Surface Area | 87.07 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 343.05145 |
| Heavy Atoms | 24 |
| Complexity | 844.55945 |
Chemical Identifiers
| CAS Number | 25745-34-0 |
|---|---|
| SMILES | COC1=C(C=CC(=C1)/C=C\2/C(=O)N(C(=O)S2)C3=CC=C(C=C3)O)O |
Product Overview
5-(4-hydroxy-3-methoxybenzylidene)-3-(4-hydroxyphenyl)-1,3-thiazolidine-2,4-dione (CAS 25745-34-0), with molecular formula C17H13NO5S and molecular weight 343.05 g/mol. IUPAC: (5Z)-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-3-(4-hydroxyphenyl)-1,3-thiazolidine-2,4-dione.
Chemical Property Profile of 5-(4-hydroxy-3-methoxybenzylidene)-3-(4-hydroxyphenyl)-1,3-thiazolidine-2,4-dione
Property Insights of 5-(4-hydroxy-3-methoxybenzylidene)-3-(4-hydroxyphenyl)-1,3-thiazolidine-2,4-dione
The XLogP value of 3.3473 indicates that 5-(4-hydroxy-3-methoxybenzylidene)-3-(4-hydroxyphenyl)-1,3-thiazolidine-2,4-dione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 87.07 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-(4-hydroxy-3-methoxybenzylidene)-3-(4-hydroxyphenyl)-1,3-thiazolidine-2,4-dione. Following Lipinski's Rule of Five, 5-(4-hydroxy-3-methoxybenzylidene)-3-(4-hydroxyphenyl)-1,3-thiazolidine-2,4-dione has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-(4-hydroxy-3-methoxybenzylidene)-3-(4-hydroxyphenyl)-1,3-thiazolidine-2,4-dione?
The CAS number of 5-(4-hydroxy-3-methoxybenzylidene)-3-(4-hydroxyphenyl)-1,3-thiazolidine-2,4-dione is 25745-34-0.
What is the molecular formula of 5-(4-hydroxy-3-methoxybenzylidene)-3-(4-hydroxyphenyl)-1,3-thiazolidine-2,4-dione?
The molecular formula of 5-(4-hydroxy-3-methoxybenzylidene)-3-(4-hydroxyphenyl)-1,3-thiazolidine-2,4-dione is C17H13NO5S.
What is the molecular weight of 5-(4-hydroxy-3-methoxybenzylidene)-3-(4-hydroxyphenyl)-1,3-thiazolidine-2,4-dione?
The molecular weight of 5-(4-hydroxy-3-methoxybenzylidene)-3-(4-hydroxyphenyl)-1,3-thiazolidine-2,4-dione is 343.05 g/mol.
Where can I buy 5-(4-hydroxy-3-methoxybenzylidene)-3-(4-hydroxyphenyl)-1,3-thiazolidine-2,4-dione?
You can request a quote for 5-(4-hydroxy-3-methoxybenzylidene)-3-(4-hydroxyphenyl)-1,3-thiazolidine-2,4-dione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-(4-hydroxy-3-methoxybenzylidene)-3-(4-hydroxyphenyl)-1,3-thiazolidine-2,4-dione?
Yes, KEHONG BIO provides custom synthesis services for 5-(4-hydroxy-3-methoxybenzylidene)-3-(4-hydroxyphenyl)-1,3-thiazolidine-2,4-dione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.