![1-[4-Fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione structure](/static/products/2567/25678-11-9.webp)
1-[4-Fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
TL;DR: 1-[4-Fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione (CAS 25678-11-9) is a chemical compound with molecular formula C10H13FN2O4 and molecular weight 244.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[4-fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Also Known As: Alovudine, 3'-Fluorothymidine, 3'-Fluorodeoxythymidine, 3'-Fluoro-3'-deoxythymidine, 3'-DEOXY-3'-FLUOROTHYMIDINE
| Molecular Formula | C10H13FN2O4 |
|---|---|
| Molecular Weight | 244.09 g/mol |
| LogP | -0.3 |
| Topological Polar Surface Area | 78.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 244.08594 |
| Heavy Atoms | 17 |
| Complexity | 385.0 |
Chemical Identifiers
| CAS Number | 25678-11-9 |
|---|---|
| SMILES | CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)F |
| InChIKey | UXCAQJAQSWSNPQ-UHFFFAOYSA-N |
Product Overview
1-[4-Fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione (CAS 25678-11-9), with molecular formula C10H13FN2O4 and molecular weight 244.09 g/mol. IUPAC: 1-[4-fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione.
Chemical Property Profile of 1-[4-Fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Property Insights of 1-[4-Fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
The XLogP value of -0.3 indicates that 1-[4-Fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 78.9 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-[4-Fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione. Following Lipinski's Rule of Five, 1-[4-Fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-[4-Fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione?
The CAS number of 1-[4-Fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione is 25678-11-9.
What is the molecular formula of 1-[4-Fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione?
The molecular formula of 1-[4-Fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione is C10H13FN2O4.
What is the molecular weight of 1-[4-Fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione?
The molecular weight of 1-[4-Fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione is 244.09 g/mol.
Where can I buy 1-[4-Fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione?
You can request a quote for 1-[4-Fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-[4-Fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione?
Yes, KEHONG BIO provides custom synthesis services for 1-[4-Fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.