angiotensin I, des-Leu(10)-
TL;DR: angiotensin I, des-Leu(10)- (CAS 25673-02-3) is a chemical compound with molecular formula C55H76N16O13 and molecular weight 1168.58 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(1S)-1-carboxy-2-(1H-imidazol-5-yl)ethyl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
Also Known As: Angiotensin I, des-leu(10)-, 10-Des-leu-angiotensin I, Angiotensin I, de-leucine(10)-, Angiotensin I, 5-L-valine-10-de-L-leucine-, (3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(1S)-1-carboxy-2-(1H-imidazol-5-yl)ethyl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
| Molecular Formula | C55H76N16O13 |
|---|---|
| Molecular Weight | 1168.58 g/mol |
| LogP | -2.2542 |
| Topological Polar Surface Area | 466.62 Ų |
| Hydrogen Bond Donors | 15 |
| Hydrogen Bond Acceptors | 15 |
| Rotatable Bonds | 32 |
| Exact Mass | 1168.5778 |
| Heavy Atoms | 84 |
| Complexity | 2901.6968 |
Chemical Identifiers
| CAS Number | 25673-02-3 |
|---|---|
| SMILES | CC(C)[C@@H](C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC2=CN=CN2)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)N[C@@H](CC5=CN=CN5)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(=O)O)N |
Product Overview
angiotensin I, des-Leu(10)- (CAS 25673-02-3), with molecular formula C55H76N16O13 and molecular weight 1168.58 g/mol. IUPAC: (3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(1S)-1-carboxy-2-(1H-imidazol-5-yl)ethyl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid.
Chemical Property Profile of angiotensin I, des-Leu(10)-
Property Insights of angiotensin I, des-Leu(10)-
The XLogP value of -2.2542 indicates that angiotensin I, des-Leu(10)- is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 466.62 Ų indicates high polarity, suggesting angiotensin I, des-Leu(10)- may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, angiotensin I, des-Leu(10)- has 15 hydrogen bond donor(s) and 15 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of angiotensin I, des-Leu(10)-?
The CAS number of angiotensin I, des-Leu(10)- is 25673-02-3.
What is the molecular formula of angiotensin I, des-Leu(10)-?
The molecular formula of angiotensin I, des-Leu(10)- is C55H76N16O13.
What is the molecular weight of angiotensin I, des-Leu(10)-?
The molecular weight of angiotensin I, des-Leu(10)- is 1168.58 g/mol.
Where can I buy angiotensin I, des-Leu(10)-?
You can request a quote for angiotensin I, des-Leu(10)- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for angiotensin I, des-Leu(10)-?
Yes, KEHONG BIO provides custom synthesis services for angiotensin I, des-Leu(10)- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.