A-Denopterin
TL;DR: A-Denopterin (CAS 25663-23-4) is a chemical compound with molecular formula C21H24N8O5 and molecular weight 468.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-2-[[4-[1-(2,4-diaminopteridin-6-yl)ethyl-methylamino]benzoyl]amino]pentanedioic acid
Also Known As: A-Denopterin, Adenopterin, A-DENOPTERIN [MI], 4-Amino-9,10-dimethyl pteroylglutamic acid, 4-amino-n10,9-dimethylpteroylglutamic acid
| Molecular Formula | C21H24N8O5 |
|---|---|
| Molecular Weight | 468.19 g/mol |
| LogP | -1.4 |
| Topological Polar Surface Area | 211.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 12 |
| Rotatable Bonds | 9 |
| Exact Mass | 468.18695 |
| Heavy Atoms | 34 |
| Complexity | 734.0 |
Chemical Identifiers
| CAS Number | 25663-23-4 |
|---|---|
| SMILES | CC(C1=CN=C2C(=N1)C(=NC(=N2)N)N)N(C)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O |
| InChIKey | PDZWMZKEQIIYKL-HQVZTVAUSA-N |
Product Overview
A-Denopterin (CAS 25663-23-4), with molecular formula C21H24N8O5 and molecular weight 468.19 g/mol. IUPAC: (2S)-2-[[4-[1-(2,4-diaminopteridin-6-yl)ethyl-methylamino]benzoyl]amino]pentanedioic acid.
Chemical Property Profile of A-Denopterin
Property Insights of A-Denopterin
The XLogP value of -1.4 indicates that A-Denopterin is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 211.0 Ų indicates high polarity, suggesting A-Denopterin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, A-Denopterin has 5 hydrogen bond donor(s) and 12 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of A-Denopterin?
The CAS number of A-Denopterin is 25663-23-4.
What is the molecular formula of A-Denopterin?
The molecular formula of A-Denopterin is C21H24N8O5.
What is the molecular weight of A-Denopterin?
The molecular weight of A-Denopterin is 468.19 g/mol.
Where can I buy A-Denopterin?
You can request a quote for A-Denopterin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for A-Denopterin?
Yes, KEHONG BIO provides custom synthesis services for A-Denopterin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.