Clobetasol 17-butyrate
TL;DR: Clobetasol 17-butyrate (CAS 25636-59-3) is a chemical compound with molecular formula C26H34ClFO5 and molecular weight 480.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(8S,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] butanoate
Also Known As: Clobetasol 17-butyrate, KST-1A3213, (9xi,11, A,16, A)-21-chloro-9-fluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl butyrate
| Molecular Formula | C26H34ClFO5 |
|---|---|
| Molecular Weight | 480.21 g/mol |
| LogP | 3.6 |
| Topological Polar Surface Area | 80.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 480.2079 |
| Heavy Atoms | 33 |
| Complexity | 945.0 |
Chemical Identifiers
| CAS Number | 25636-59-3 |
|---|---|
| SMILES | CCCC(=O)O[C@@]1([C@H](C[C@@H]2[C@@]1(C[C@@H](C3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)C)C(=O)CCl |
| InChIKey | DERCOWNWEPPIHD-AKBCLJBMSA-N |
Product Overview
Clobetasol 17-butyrate (CAS 25636-59-3), with molecular formula C26H34ClFO5 and molecular weight 480.21 g/mol. IUPAC: [(8S,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] butanoate.
Chemical Property Profile of Clobetasol 17-butyrate
Property Insights of Clobetasol 17-butyrate
The XLogP value of 3.6 indicates that Clobetasol 17-butyrate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 80.7 Ų falls within the moderate polarity range, balancing permeability and solubility for Clobetasol 17-butyrate. Following Lipinski's Rule of Five, Clobetasol 17-butyrate has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Clobetasol 17-butyrate?
The CAS number of Clobetasol 17-butyrate is 25636-59-3.
What is the molecular formula of Clobetasol 17-butyrate?
The molecular formula of Clobetasol 17-butyrate is C26H34ClFO5.
What is the molecular weight of Clobetasol 17-butyrate?
The molecular weight of Clobetasol 17-butyrate is 480.21 g/mol.
Where can I buy Clobetasol 17-butyrate?
You can request a quote for Clobetasol 17-butyrate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Clobetasol 17-butyrate?
Yes, KEHONG BIO provides custom synthesis services for Clobetasol 17-butyrate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.