![N-[2,2,2-Trifluoro-1-[(6-methyl-2-pyridyl)amino]-1-(trifluoromethyl)ethyl]nicotinamide structure](/static/products/256/256325-84-5.png)
N-[2,2,2-Trifluoro-1-[(6-methyl-2-pyridyl)amino]-1-(trifluoromethyl)ethyl]nicotinamide
TL;DR: N-[2,2,2-Trifluoro-1-[(6-methyl-2-pyridyl)amino]-1-(trifluoromethyl)ethyl]nicotinamide (CAS 256325-84-5) is a chemical compound with molecular formula C15H12F6N4O and molecular weight 378.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[1,1,1,3,3,3-hexafluoro-2-[(6-methyl-2-pyridinyl)amino]propan-2-yl]pyridine-3-carboxamide
Also Known As: N-[2,2,2-Trifluoro-1-[(6-methyl-2-pyridyl)amino]-1-(trifluoromethyl)ethyl]nicotinamide, N-(1,1,1,3,3,3-hexafluoro-2-((6-methylpyridin-2-yl)amino)propan-2-yl)nicotinamide, N-[1,1,1,3,3,3-hexafluoro-2-[(6-methylpyridin-2-yl)amino]propan-2-yl]pyridine-3-carboxamide, N-[2,2,2-Trifluoro-1-[(6-methyl-2-pyridinyl)amino]-1-(trifluoromethyl)ethyl]nicotinamide #, N-{1,1,1,3,3,3-hexafluoro-2-[(6-methylpyridin-2-yl)amino]propan-2-yl}pyridine-3-carboxamide
| Molecular Formula | C15H12F6N4O |
|---|---|
| Molecular Weight | 378.09 g/mol |
| LogP | 4.2 |
| Topological Polar Surface Area | 66.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 4 |
| Exact Mass | 378.09152 |
| Heavy Atoms | 26 |
| Complexity | 482.0 |
Chemical Identifiers
| CAS Number | 256325-84-5 |
|---|---|
| SMILES | CC1=NC(=CC=C1)NC(C(F)(F)F)(C(F)(F)F)NC(=O)C2=CN=CC=C2 |
| InChIKey | HHTSVKDWMQUUEZ-UHFFFAOYSA-N |
Product Overview
N-[2,2,2-Trifluoro-1-[(6-methyl-2-pyridyl)amino]-1-(trifluoromethyl)ethyl]nicotinamide (CAS 256325-84-5), with molecular formula C15H12F6N4O and molecular weight 378.09 g/mol. IUPAC: N-[1,1,1,3,3,3-hexafluoro-2-[(6-methyl-2-pyridinyl)amino]propan-2-yl]pyridine-3-carboxamide.
Chemical Property Profile of N-[2,2,2-Trifluoro-1-[(6-methyl-2-pyridyl)amino]-1-(trifluoromethyl)ethyl]nicotinamide
Property Insights of N-[2,2,2-Trifluoro-1-[(6-methyl-2-pyridyl)amino]-1-(trifluoromethyl)ethyl]nicotinamide
The XLogP value of 4.2 indicates that N-[2,2,2-Trifluoro-1-[(6-methyl-2-pyridyl)amino]-1-(trifluoromethyl)ethyl]nicotinamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 66.9 Ų falls within the moderate polarity range, balancing permeability and solubility for N-[2,2,2-Trifluoro-1-[(6-methyl-2-pyridyl)amino]-1-(trifluoromethyl)ethyl]nicotinamide. Following Lipinski's Rule of Five, N-[2,2,2-Trifluoro-1-[(6-methyl-2-pyridyl)amino]-1-(trifluoromethyl)ethyl]nicotinamide has 2 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-[2,2,2-Trifluoro-1-[(6-methyl-2-pyridyl)amino]-1-(trifluoromethyl)ethyl]nicotinamide?
The CAS number of N-[2,2,2-Trifluoro-1-[(6-methyl-2-pyridyl)amino]-1-(trifluoromethyl)ethyl]nicotinamide is 256325-84-5.
What is the molecular formula of N-[2,2,2-Trifluoro-1-[(6-methyl-2-pyridyl)amino]-1-(trifluoromethyl)ethyl]nicotinamide?
The molecular formula of N-[2,2,2-Trifluoro-1-[(6-methyl-2-pyridyl)amino]-1-(trifluoromethyl)ethyl]nicotinamide is C15H12F6N4O.
What is the molecular weight of N-[2,2,2-Trifluoro-1-[(6-methyl-2-pyridyl)amino]-1-(trifluoromethyl)ethyl]nicotinamide?
The molecular weight of N-[2,2,2-Trifluoro-1-[(6-methyl-2-pyridyl)amino]-1-(trifluoromethyl)ethyl]nicotinamide is 378.09 g/mol.
Where can I buy N-[2,2,2-Trifluoro-1-[(6-methyl-2-pyridyl)amino]-1-(trifluoromethyl)ethyl]nicotinamide?
You can request a quote for N-[2,2,2-Trifluoro-1-[(6-methyl-2-pyridyl)amino]-1-(trifluoromethyl)ethyl]nicotinamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-[2,2,2-Trifluoro-1-[(6-methyl-2-pyridyl)amino]-1-(trifluoromethyl)ethyl]nicotinamide?
Yes, KEHONG BIO provides custom synthesis services for N-[2,2,2-Trifluoro-1-[(6-methyl-2-pyridyl)amino]-1-(trifluoromethyl)ethyl]nicotinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.