Ethyl 2-(3-chloroanilino)-3,3,3-trifluoro-2-nicotinamidopropionate structure

Ethyl 2-(3-chloroanilino)-3,3,3-trifluoro-2-nicotinamidopropionate

TL;DR: Ethyl 2-(3-chloroanilino)-3,3,3-trifluoro-2-nicotinamidopropionate (CAS 256325-74-3) is a chemical compound with molecular formula C17H15ClF3N3O3 and molecular weight 401.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

ethyl 2-(3-chloroanilino)-3,3,3-trifluoro-2-(pyridine-3-carbonylamino)propanoate

Also Known As: Ethyl 2-(3-chloroanilino)-3,3,3-trifluoro-2-nicotinamidopropionate, ethyl 2-[(3-chlorophenyl)amino]-3,3,3-trifluoro-N-(pyridin-3-ylcarbonyl)alaninate, ethyl 2-((3-chlorophenyl)amino)-3,3,3-trifluoro-2-(nicotinamido)propanoate, ethyl 2-(3-chloroanilino)-3,3,3-trifluoro-2-(pyridine-3-carbonylamino)propanoate, Ethyl 2-(3-chloroanilino)-3,3,3-trifluoro-2-[(3-pyridinylcarbonyl)amino]propanoate #

CAS: 256325-74-3
Molecular Formula C17H15ClF3N3O3
Molecular Weight 401.08 g/mol
LogP 4.3
Topological Polar Surface Area 80.3 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 8
Rotatable Bonds 7
Exact Mass 401.0754
Heavy Atoms 27
Complexity 535.0

Chemical Identifiers

CAS Number 256325-74-3
SMILES CCOC(=O)C(C(F)(F)F)(NC1=CC(=CC=C1)Cl)NC(=O)C2=CN=CC=C2
InChIKey JAIMCKOJJYZFAX-UHFFFAOYSA-N

Product Overview

Ethyl 2-(3-chloroanilino)-3,3,3-trifluoro-2-nicotinamidopropionate (CAS 256325-74-3), with molecular formula C17H15ClF3N3O3 and molecular weight 401.08 g/mol. IUPAC: ethyl 2-(3-chloroanilino)-3,3,3-trifluoro-2-(pyridine-3-carbonylamino)propanoate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Ethyl 2-(3-chloroanilino)-3,3,3-trifluoro-2-nicotinamidopropionate

XLogP
4.3
TPSA (Topological Polar Surface Area)
80.3
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
8
Rotatable Bonds
7
Heavy Atoms
27
Complexity
535.0
Exact Mass
401.0754
Monoisotopic Mass
401.0754
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Ethyl 2-(3-chloroanilino)-3,3,3-trifluoro-2-nicotinamidopropionate

The XLogP value of 4.3 indicates that Ethyl 2-(3-chloroanilino)-3,3,3-trifluoro-2-nicotinamidopropionate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 80.3 Ų falls within the moderate polarity range, balancing permeability and solubility for Ethyl 2-(3-chloroanilino)-3,3,3-trifluoro-2-nicotinamidopropionate. Following Lipinski's Rule of Five, Ethyl 2-(3-chloroanilino)-3,3,3-trifluoro-2-nicotinamidopropionate has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Ethyl 2-(3-chloroanilino)-3,3,3-trifluoro-2-nicotinamidopropionate?

The CAS number of Ethyl 2-(3-chloroanilino)-3,3,3-trifluoro-2-nicotinamidopropionate is 256325-74-3.

What is the molecular formula of Ethyl 2-(3-chloroanilino)-3,3,3-trifluoro-2-nicotinamidopropionate?

The molecular formula of Ethyl 2-(3-chloroanilino)-3,3,3-trifluoro-2-nicotinamidopropionate is C17H15ClF3N3O3.

What is the molecular weight of Ethyl 2-(3-chloroanilino)-3,3,3-trifluoro-2-nicotinamidopropionate?

The molecular weight of Ethyl 2-(3-chloroanilino)-3,3,3-trifluoro-2-nicotinamidopropionate is 401.08 g/mol.

Where can I buy Ethyl 2-(3-chloroanilino)-3,3,3-trifluoro-2-nicotinamidopropionate?

You can request a quote for Ethyl 2-(3-chloroanilino)-3,3,3-trifluoro-2-nicotinamidopropionate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Ethyl 2-(3-chloroanilino)-3,3,3-trifluoro-2-nicotinamidopropionate?

Yes, KEHONG BIO provides custom synthesis services for Ethyl 2-(3-chloroanilino)-3,3,3-trifluoro-2-nicotinamidopropionate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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