2-Amino-5-phenyl-4-(trifluoromethyl)thiazole
TL;DR: 2-Amino-5-phenyl-4-(trifluoromethyl)thiazole (CAS 255833-34-2) is a chemical compound with molecular formula C10H7F3N2S and molecular weight 244.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-phenyl-4-(trifluoromethyl)-1,3-thiazol-2-amine
Also Known As: 2-amino-5-phenyl-4-(trifluoromethyl)thiazole, 5-phenyl-4-(trifluoromethyl)thiazol-2-amine, 5-phenyl-4-(trifluoromethyl)-1,3-thiazol-2-amine, 5-phenyl-4-(trifluoromethyl)-1,3-thiazole-2-ylamine
| Molecular Formula | C10H7F3N2S |
|---|---|
| Molecular Weight | 244.03 g/mol |
| LogP | 3.4111 |
| Topological Polar Surface Area | 38.91 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 244.0282 |
| Heavy Atoms | 16 |
| Complexity | 490.5104 |
Chemical Identifiers
| CAS Number | 255833-34-2 |
|---|---|
| SMILES | C1=CC=C(C=C1)C2=C(N=C(S2)N)C(F)(F)F |
Product Overview
2-Amino-5-phenyl-4-(trifluoromethyl)thiazole (CAS 255833-34-2), with molecular formula C10H7F3N2S and molecular weight 244.03 g/mol. IUPAC: 5-phenyl-4-(trifluoromethyl)-1,3-thiazol-2-amine.
Chemical Property Profile of 2-Amino-5-phenyl-4-(trifluoromethyl)thiazole
Property Insights of 2-Amino-5-phenyl-4-(trifluoromethyl)thiazole
The XLogP value of 3.4111 indicates that 2-Amino-5-phenyl-4-(trifluoromethyl)thiazole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 38.91 Ų, 2-Amino-5-phenyl-4-(trifluoromethyl)thiazole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-Amino-5-phenyl-4-(trifluoromethyl)thiazole has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-Amino-5-phenyl-4-(trifluoromethyl)thiazole?
The CAS number of 2-Amino-5-phenyl-4-(trifluoromethyl)thiazole is 255833-34-2.
What is the molecular formula of 2-Amino-5-phenyl-4-(trifluoromethyl)thiazole?
The molecular formula of 2-Amino-5-phenyl-4-(trifluoromethyl)thiazole is C10H7F3N2S.
What is the molecular weight of 2-Amino-5-phenyl-4-(trifluoromethyl)thiazole?
The molecular weight of 2-Amino-5-phenyl-4-(trifluoromethyl)thiazole is 244.03 g/mol.
Where can I buy 2-Amino-5-phenyl-4-(trifluoromethyl)thiazole?
You can request a quote for 2-Amino-5-phenyl-4-(trifluoromethyl)thiazole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-Amino-5-phenyl-4-(trifluoromethyl)thiazole?
Yes, KEHONG BIO provides custom synthesis services for 2-Amino-5-phenyl-4-(trifluoromethyl)thiazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.