N-(5-Oxo-L-prolyl)-L-histidinohydrazide
TL;DR: N-(5-Oxo-L-prolyl)-L-histidinohydrazide (CAS 25575-89-7) is a chemical compound with molecular formula C11H16N6O3 and molecular weight 280.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-N-[(2S)-1-hydrazinyl-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Also Known As: pyroglutamylhistidine hydrazide, L-pyroglutamyl-L-histidine hydrazide, N-(5-Oxo-L-prolyl)-L-histidinohydrazide, 5-Oxo-L-Pro-L-His-NHNH2, (2S)-N-[(2S)-1-hydrazinyl-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
| Molecular Formula | C11H16N6O3 |
|---|---|
| Molecular Weight | 280.13 g/mol |
| LogP | -2.9 |
| Topological Polar Surface Area | 142.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 280.1284 |
| Heavy Atoms | 20 |
| Complexity | 402.0 |
Chemical Identifiers
| CAS Number | 25575-89-7 |
|---|---|
| SMILES | C1CC(=O)N[C@@H]1C(=O)N[C@@H](CC2=CN=CN2)C(=O)NN |
| InChIKey | ZNCVCDONTDKDNY-YUMQZZPRSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
N-(5-Oxo-L-prolyl)-L-histidinohydrazide (CAS 25575-89-7), with molecular formula C11H16N6O3 and molecular weight 280.13 g/mol. IUPAC: (2S)-N-[(2S)-1-hydrazinyl-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide.
Chemical Property Profile of N-(5-Oxo-L-prolyl)-L-histidinohydrazide
Property Insights of N-(5-Oxo-L-prolyl)-L-histidinohydrazide
The XLogP value of -2.9 indicates that N-(5-Oxo-L-prolyl)-L-histidinohydrazide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 142.0 Ų indicates high polarity, suggesting N-(5-Oxo-L-prolyl)-L-histidinohydrazide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, N-(5-Oxo-L-prolyl)-L-histidinohydrazide has 5 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(5-Oxo-L-prolyl)-L-histidinohydrazide?
The CAS number of N-(5-Oxo-L-prolyl)-L-histidinohydrazide is 25575-89-7.
What is the molecular formula of N-(5-Oxo-L-prolyl)-L-histidinohydrazide?
The molecular formula of N-(5-Oxo-L-prolyl)-L-histidinohydrazide is C11H16N6O3.
What is the molecular weight of N-(5-Oxo-L-prolyl)-L-histidinohydrazide?
The molecular weight of N-(5-Oxo-L-prolyl)-L-histidinohydrazide is 280.13 g/mol.
Where can I buy N-(5-Oxo-L-prolyl)-L-histidinohydrazide?
You can request a quote for N-(5-Oxo-L-prolyl)-L-histidinohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(5-Oxo-L-prolyl)-L-histidinohydrazide?
Yes, KEHONG BIO provides custom synthesis services for N-(5-Oxo-L-prolyl)-L-histidinohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.