右氯苯那敏
TL;DR: 右氯苯那敏 (CAS 25523-97-1) is a chemical compound with molecular formula C16H19ClN2 and molecular weight 274.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
右氯苯那敏
(3S)-3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine
Also Known As: DEXCHLORPHENIRAMINE, D-Chlorpheniramine, Phendextro, Chlo-amine, Dexclorfeniramina
| Molecular Formula | C16H19ClN2 |
|---|---|
| Molecular Weight | 274.12 g/mol |
| LogP | 3.4 |
| Topological Polar Surface Area | 16.1 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 5 |
| Exact Mass | 274.1237 |
| Heavy Atoms | 19 |
| Complexity | 249.0 |
| Melting Point | CRYSTALS FROM ETHYL ACETATE; MP: 113-115 °C; SPECIFIC OPTICAL ROTATION (DIMETHYLFORMAMIDE): +44.3 DEG @ 25 °C/D, PH OF 1% SOLN 4-5 /D-FORM, MALEATE/ |
| Boiling Point | 142 °C @ 1.0 mm Hg /Racemate/ |
| Solubility | WHITE CRYSTALLINE POWDER; ODORLESS; 1 G SOL IN 4 ML WATER; SOL IN ALC, CHLOROFORM; SLIGHTLY SOL IN BENZENE, ETHER /MALEATE/ |
| Refractive Index | 1.509 (ALPHA); 1.564 (BETA); 1.683 (GAMMA); OPTIC SIGN: + /MALEATE/ |
Chemical Identifiers
| CAS Number | 25523-97-1 |
|---|---|
| SMILES | CN(C)CC[C@@H](C1=CC=C(C=C1)Cl)C2=CC=CC=N2 |
| InChIKey | SOYKEARSMXGVTM-HNNXBMFYSA-N |
Patent-Derived Application Labels
Derived from 14 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
右氯苯那敏 (CAS 25523-97-1), with molecular formula C16H19ClN2 and molecular weight 274.12 g/mol. IUPAC: (3S)-3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine.
Chemical Property Profile of 右氯苯那敏
Property Insights of 右氯苯那敏
The XLogP value of 3.4 indicates that 右氯苯那敏 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 16.1 Ų, 右氯苯那敏 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 右氯苯那敏 has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 右氯苯那敏?
The CAS number of 右氯苯那敏 is 25523-97-1.
What is the molecular formula of 右氯苯那敏?
The molecular formula of 右氯苯那敏 is C16H19ClN2.
What is the molecular weight of 右氯苯那敏?
The molecular weight of 右氯苯那敏 is 274.12 g/mol.
Where can I buy 右氯苯那敏?
You can request a quote for 右氯苯那敏 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 右氯苯那敏?
Yes, KEHONG BIO provides custom synthesis services for 右氯苯那敏 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.