Dota-4AMP structure

Dota-4AMP

TL;DR: Dota-4AMP (CAS 254444-71-8) is a chemical compound with molecular formula C20H44N8O16P4 and molecular weight 776.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[[2-[4,7,10-tris[2-oxo-2-(phosphonomethylamino)ethyl]-1,4,7,10-tetrazacyclododec-1-yl]acetyl]amino]methylphosphonic acid

Also Known As: DOTA-4AMP, HY-W802013, J1.248.729K, 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrakis(acetamido-methylenephosphonic acid), 1,4,7,10-Tetrakis(phosphonomethylcarbamoylmethyl)-1,4,7,10-tetraazacyclododecane

CAS: 254444-71-8
Molecular Formula C20H44N8O16P4
Molecular Weight 776.18 g/mol
LogP -5.7864
Topological Polar Surface Area 359.48 Ų
Hydrogen Bond Donors 12
Hydrogen Bond Acceptors 12
Rotatable Bonds 16
Exact Mass 776.18256
Heavy Atoms 48
Complexity 1077.9524

Chemical Identifiers

CAS Number 254444-71-8
SMILES C1CN(CCN(CCN(CCN1CC(=O)NCP(=O)(O)O)CC(=O)NCP(=O)(O)O)CC(=O)NCP(=O)(O)O)CC(=O)NCP(=O)(O)O

Product Overview

Dota-4AMP (CAS 254444-71-8), with molecular formula C20H44N8O16P4 and molecular weight 776.18 g/mol. IUPAC: [[2-[4,7,10-tris[2-oxo-2-(phosphonomethylamino)ethyl]-1,4,7,10-tetrazacyclododec-1-yl]acetyl]amino]methylphosphonic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Dota-4AMP

XLogP
-5.7864
TPSA (Topological Polar Surface Area)
359.48
Hydrogen Bond Donors
12
Hydrogen Bond Acceptors
12
Rotatable Bonds
16
Heavy Atoms
48
Complexity
1077.9524
Exact Mass
776.18256
Monoisotopic Mass
776.18256
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Dota-4AMP

The XLogP value of -5.7864 indicates that Dota-4AMP is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 359.48 Ų indicates high polarity, suggesting Dota-4AMP may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Dota-4AMP has 12 hydrogen bond donor(s) and 12 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Dota-4AMP?

The CAS number of Dota-4AMP is 254444-71-8.

What is the molecular formula of Dota-4AMP?

The molecular formula of Dota-4AMP is C20H44N8O16P4.

What is the molecular weight of Dota-4AMP?

The molecular weight of Dota-4AMP is 776.18 g/mol.

Where can I buy Dota-4AMP?

You can request a quote for Dota-4AMP directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Dota-4AMP?

Yes, KEHONG BIO provides custom synthesis services for Dota-4AMP and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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