Apremilast Impurity 165
TL;DR: Apremilast Impurity 165 (CAS 253168-87-5) is a chemical compound with molecular formula C22H24N2O7S and molecular weight 460.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-5-yl]acetamide
Also Known As: Apremilast Impurity 165, N-(2-(1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl)-1,3-dioxoisoindolin-5-yl)acetaMide, 2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-5-acetamidoisoindoline-1,3-dione, Acetamide, N-[2-[1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-, N-[2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-5-yl]acetamide
| Molecular Formula | C22H24N2O7S |
|---|---|
| Molecular Weight | 460.13 g/mol |
| LogP | 2.4342 |
| Topological Polar Surface Area | 119.08 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 8 |
| Exact Mass | 460.13043 |
| Heavy Atoms | 32 |
| Complexity | 1190.7606 |
Chemical Identifiers
| CAS Number | 253168-87-5 |
|---|---|
| SMILES | CCOC1=C(C=CC(=C1)C(CS(=O)(=O)C)N2C(=O)C3=C(C2=O)C=C(C=C3)NC(=O)C)OC |
Product Overview
Apremilast Impurity 165 (CAS 253168-87-5), with molecular formula C22H24N2O7S and molecular weight 460.13 g/mol. IUPAC: N-[2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-5-yl]acetamide.
Chemical Property Profile of Apremilast Impurity 165
Property Insights of Apremilast Impurity 165
The XLogP value of 2.4342 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Apremilast Impurity 165. The TPSA of 119.08 Ų falls within the moderate polarity range, balancing permeability and solubility for Apremilast Impurity 165. Following Lipinski's Rule of Five, Apremilast Impurity 165 has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Apremilast Impurity 165?
The CAS number of Apremilast Impurity 165 is 253168-87-5.
What is the molecular formula of Apremilast Impurity 165?
The molecular formula of Apremilast Impurity 165 is C22H24N2O7S.
What is the molecular weight of Apremilast Impurity 165?
The molecular weight of Apremilast Impurity 165 is 460.13 g/mol.
Where can I buy Apremilast Impurity 165?
You can request a quote for Apremilast Impurity 165 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Apremilast Impurity 165?
Yes, KEHONG BIO provides custom synthesis services for Apremilast Impurity 165 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.