4-Chloro-2-(2-hydroxyphenyl)quinazoline
TL;DR: 4-Chloro-2-(2-hydroxyphenyl)quinazoline (CAS 25171-36-2) is a chemical compound with molecular formula C14H9ClN2O and molecular weight 256.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(4-chloroquinazolin-2-yl)phenol
Also Known As: 2-(4-chloroquinazolin-2-yl)phenol, 4-chloro-2-(2-hydroxyphenyl)quinazoline, 2-(4-Chloro-quinazolin-2-yl)-phenol, 4-chloro-2-(o-hydroxyphenyl)quinazoline, 4-chloro-2-(4-chloroquinazolin-2-yl)phenol
| Molecular Formula | C14H9ClN2O |
|---|---|
| Molecular Weight | 256.04 g/mol |
| LogP | 3.6558 |
| Topological Polar Surface Area | 46.01 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 256.04034 |
| Heavy Atoms | 18 |
| Complexity | 727.81586 |
Chemical Identifiers
| CAS Number | 25171-36-2 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C(=NC(=N2)C3=CC=CC=C3O)Cl |
Product Overview
4-Chloro-2-(2-hydroxyphenyl)quinazoline (CAS 25171-36-2), with molecular formula C14H9ClN2O and molecular weight 256.04 g/mol. IUPAC: 2-(4-chloroquinazolin-2-yl)phenol.
Chemical Property Profile of 4-Chloro-2-(2-hydroxyphenyl)quinazoline
Property Insights of 4-Chloro-2-(2-hydroxyphenyl)quinazoline
The XLogP value of 3.6558 indicates that 4-Chloro-2-(2-hydroxyphenyl)quinazoline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 46.01 Ų, 4-Chloro-2-(2-hydroxyphenyl)quinazoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Chloro-2-(2-hydroxyphenyl)quinazoline has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Chloro-2-(2-hydroxyphenyl)quinazoline?
The CAS number of 4-Chloro-2-(2-hydroxyphenyl)quinazoline is 25171-36-2.
What is the molecular formula of 4-Chloro-2-(2-hydroxyphenyl)quinazoline?
The molecular formula of 4-Chloro-2-(2-hydroxyphenyl)quinazoline is C14H9ClN2O.
What is the molecular weight of 4-Chloro-2-(2-hydroxyphenyl)quinazoline?
The molecular weight of 4-Chloro-2-(2-hydroxyphenyl)quinazoline is 256.04 g/mol.
Where can I buy 4-Chloro-2-(2-hydroxyphenyl)quinazoline?
You can request a quote for 4-Chloro-2-(2-hydroxyphenyl)quinazoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Chloro-2-(2-hydroxyphenyl)quinazoline?
Yes, KEHONG BIO provides custom synthesis services for 4-Chloro-2-(2-hydroxyphenyl)quinazoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.