1-(2,2,2-Trifluoro-1-hydroxyethyl)-2-naphthol
TL;DR: 1-(2,2,2-Trifluoro-1-hydroxyethyl)-2-naphthol (CAS 251352-70-2) is a chemical compound with molecular formula C12H9F3O2 and molecular weight 242.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(2,2,2-trifluoro-1-hydroxyethyl)naphthalen-2-ol
Also Known As: 1-(2,2,2-trifluoro-1-hydroxyethyl)naphthalen-2-ol, 1-(2,2,2-Trifluoro-1-hydroxyethyl)-2-naphthol, J1.468.389E, 1-(2,2,2-trifluoro-1-hydroxy-ethyl)naphthalen-2-ol
| Molecular Formula | C12H9F3O2 |
|---|---|
| Molecular Weight | 242.06 g/mol |
| LogP | 3.1411 |
| Topological Polar Surface Area | 40.46 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 242.05547 |
| Heavy Atoms | 17 |
| Complexity | 548.9323 |
Chemical Identifiers
| CAS Number | 251352-70-2 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C=CC(=C2C(C(F)(F)F)O)O |
Product Overview
1-(2,2,2-Trifluoro-1-hydroxyethyl)-2-naphthol (CAS 251352-70-2), with molecular formula C12H9F3O2 and molecular weight 242.06 g/mol. IUPAC: 1-(2,2,2-trifluoro-1-hydroxyethyl)naphthalen-2-ol.
Chemical Property Profile of 1-(2,2,2-Trifluoro-1-hydroxyethyl)-2-naphthol
Property Insights of 1-(2,2,2-Trifluoro-1-hydroxyethyl)-2-naphthol
The XLogP value of 3.1411 indicates that 1-(2,2,2-Trifluoro-1-hydroxyethyl)-2-naphthol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.46 Ų, 1-(2,2,2-Trifluoro-1-hydroxyethyl)-2-naphthol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(2,2,2-Trifluoro-1-hydroxyethyl)-2-naphthol has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(2,2,2-Trifluoro-1-hydroxyethyl)-2-naphthol?
The CAS number of 1-(2,2,2-Trifluoro-1-hydroxyethyl)-2-naphthol is 251352-70-2.
What is the molecular formula of 1-(2,2,2-Trifluoro-1-hydroxyethyl)-2-naphthol?
The molecular formula of 1-(2,2,2-Trifluoro-1-hydroxyethyl)-2-naphthol is C12H9F3O2.
What is the molecular weight of 1-(2,2,2-Trifluoro-1-hydroxyethyl)-2-naphthol?
The molecular weight of 1-(2,2,2-Trifluoro-1-hydroxyethyl)-2-naphthol is 242.06 g/mol.
Where can I buy 1-(2,2,2-Trifluoro-1-hydroxyethyl)-2-naphthol?
You can request a quote for 1-(2,2,2-Trifluoro-1-hydroxyethyl)-2-naphthol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(2,2,2-Trifluoro-1-hydroxyethyl)-2-naphthol?
Yes, KEHONG BIO provides custom synthesis services for 1-(2,2,2-Trifluoro-1-hydroxyethyl)-2-naphthol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.