10H-053
TL;DR: 10H-053 (CAS 251307-17-2) is a chemical compound with molecular formula C20H12ClF3N4O and molecular weight 416.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(4-chlorophenyl)-3-phenyl-6-(trifluoromethyl)pyrazolo[4,3-b]pyridine-1-carboxamide
Also Known As: 10H-053, N-(4-chlorophenyl)-3-phenyl-6-(trifluoromethyl)-1H-pyrazolo[4,3-b]pyridine-1-carboxamide, N-(4-chlorophenyl)-3-phenyl-6-(trifluoromethyl)pyrazolo[4,3-b]pyridine-1-carboxamide
| Molecular Formula | C20H12ClF3N4O |
|---|---|
| Molecular Weight | 416.07 g/mol |
| LogP | 5.8507 |
| Topological Polar Surface Area | 59.81 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 416.0652 |
| Heavy Atoms | 29 |
| Complexity | 1188.3036 |
Chemical Identifiers
| CAS Number | 251307-17-2 |
|---|---|
| SMILES | C1=CC=C(C=C1)C2=NN(C3=C2N=CC(=C3)C(F)(F)F)C(=O)NC4=CC=C(C=C4)Cl |
Product Overview
10H-053 (CAS 251307-17-2), with molecular formula C20H12ClF3N4O and molecular weight 416.07 g/mol. IUPAC: N-(4-chlorophenyl)-3-phenyl-6-(trifluoromethyl)pyrazolo[4,3-b]pyridine-1-carboxamide.
Chemical Property Profile of 10H-053
Property Insights of 10H-053
The XLogP value of 5.8507 indicates that 10H-053 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.81 Ų, 10H-053 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 10H-053 has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 10H-053?
The CAS number of 10H-053 is 251307-17-2.
What is the molecular formula of 10H-053?
The molecular formula of 10H-053 is C20H12ClF3N4O.
What is the molecular weight of 10H-053?
The molecular weight of 10H-053 is 416.07 g/mol.
Where can I buy 10H-053?
You can request a quote for 10H-053 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 10H-053?
Yes, KEHONG BIO provides custom synthesis services for 10H-053 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.