![methyl 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-hydroxypyrrolidine-2-carboxylate structure](/static/products/2510/251097-80-0.webp)
methyl 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-hydroxypyrrolidine-2-carboxylate
TL;DR: methyl 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-hydroxypyrrolidine-2-carboxylate (CAS 251097-80-0) is a chemical compound with molecular formula C12H12ClF3N2O3 and molecular weight 324.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
methyl 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-4-hydroxypyrrolidine-2-carboxylate
Also Known As: methyl 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-hydroxypyrrolidine-2-carboxylate, methyl 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-4-hydroxy-2-pyrrolidinecarboxylate, methyl 1-[3-chloro-5-(trifluoromethyl)-2-pyridyl]-4-hydroxy-pyrrolidine-2-carboxylate, Methyl 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-hydroxy-pyrrolidine-2-carboxylate, Methyl 1-3-chloro-5-(trifluoromethyl)-2-pyridinyl-4-hydroxy-2-pyrrolidinecarboxylate
| Molecular Formula | C12H12ClF3N2O3 |
|---|---|
| Molecular Weight | 324.05 g/mol |
| LogP | 1.8664 |
| Topological Polar Surface Area | 62.66 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 324.04886 |
| Heavy Atoms | 21 |
| Complexity | 553.0394 |
Chemical Identifiers
| CAS Number | 251097-80-0 |
|---|---|
| SMILES | COC(=O)C1CC(CN1C2=C(C=C(C=N2)C(F)(F)F)Cl)O |
Product Overview
methyl 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-hydroxypyrrolidine-2-carboxylate (CAS 251097-80-0), with molecular formula C12H12ClF3N2O3 and molecular weight 324.05 g/mol. IUPAC: methyl 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-4-hydroxypyrrolidine-2-carboxylate.
Chemical Property Profile of methyl 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-hydroxypyrrolidine-2-carboxylate
Property Insights of methyl 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-hydroxypyrrolidine-2-carboxylate
The XLogP value of 1.8664 suggests moderate lipophilicity, balancing water solubility and membrane permeability for methyl 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-hydroxypyrrolidine-2-carboxylate. The TPSA of 62.66 Ų falls within the moderate polarity range, balancing permeability and solubility for methyl 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-hydroxypyrrolidine-2-carboxylate. Following Lipinski's Rule of Five, methyl 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-hydroxypyrrolidine-2-carboxylate has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of methyl 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-hydroxypyrrolidine-2-carboxylate?
The CAS number of methyl 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-hydroxypyrrolidine-2-carboxylate is 251097-80-0.
What is the molecular formula of methyl 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-hydroxypyrrolidine-2-carboxylate?
The molecular formula of methyl 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-hydroxypyrrolidine-2-carboxylate is C12H12ClF3N2O3.
What is the molecular weight of methyl 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-hydroxypyrrolidine-2-carboxylate?
The molecular weight of methyl 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-hydroxypyrrolidine-2-carboxylate is 324.05 g/mol.
Where can I buy methyl 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-hydroxypyrrolidine-2-carboxylate?
You can request a quote for methyl 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-hydroxypyrrolidine-2-carboxylate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for methyl 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-hydroxypyrrolidine-2-carboxylate?
Yes, KEHONG BIO provides custom synthesis services for methyl 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-hydroxypyrrolidine-2-carboxylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.