5-Amino-1-(4-fluorophenyl)-4-(3-(2,3-dihydroxypropoxy)benzoyl)pyrazole
TL;DR: 5-Amino-1-(4-fluorophenyl)-4-(3-(2,3-dihydroxypropoxy)benzoyl)pyrazole (CAS 249937-52-8) is a chemical compound with molecular formula C19H18FN3O4 and molecular weight 371.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[5-amino-1-(4-fluorophenyl)pyrazol-4-yl]-[3-(2,3-dihydroxypropoxy)phenyl]methanone
Also Known As: 2gfs, SYD003, EX-A13907, J2.282.771E, (5-Amino-1-(4-fluoro-phenyl)-1H-pyrazol-4-yl)-(3-(2,3-dihydroxy-propoxy)-phenyl)-methanone
| Molecular Formula | C19H18FN3O4 |
|---|---|
| Molecular Weight | 371.13 g/mol |
| LogP | 1.5566 |
| Topological Polar Surface Area | 110.6 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Exact Mass | 371.12814 |
| Heavy Atoms | 27 |
| Complexity | 940.38275 |
Chemical Identifiers
| CAS Number | 249937-52-8 |
|---|---|
| SMILES | C1=CC(=CC(=C1)OCC(CO)O)C(=O)C2=C(N(N=C2)C3=CC=C(C=C3)F)N |
Product Overview
5-Amino-1-(4-fluorophenyl)-4-(3-(2,3-dihydroxypropoxy)benzoyl)pyrazole (CAS 249937-52-8), with molecular formula C19H18FN3O4 and molecular weight 371.13 g/mol. IUPAC: [5-amino-1-(4-fluorophenyl)pyrazol-4-yl]-[3-(2,3-dihydroxypropoxy)phenyl]methanone.
Chemical Property Profile of 5-Amino-1-(4-fluorophenyl)-4-(3-(2,3-dihydroxypropoxy)benzoyl)pyrazole
Property Insights of 5-Amino-1-(4-fluorophenyl)-4-(3-(2,3-dihydroxypropoxy)benzoyl)pyrazole
The XLogP value of 1.5566 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5-Amino-1-(4-fluorophenyl)-4-(3-(2,3-dihydroxypropoxy)benzoyl)pyrazole. The TPSA of 110.6 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-Amino-1-(4-fluorophenyl)-4-(3-(2,3-dihydroxypropoxy)benzoyl)pyrazole. Following Lipinski's Rule of Five, 5-Amino-1-(4-fluorophenyl)-4-(3-(2,3-dihydroxypropoxy)benzoyl)pyrazole has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-Amino-1-(4-fluorophenyl)-4-(3-(2,3-dihydroxypropoxy)benzoyl)pyrazole?
The CAS number of 5-Amino-1-(4-fluorophenyl)-4-(3-(2,3-dihydroxypropoxy)benzoyl)pyrazole is 249937-52-8.
What is the molecular formula of 5-Amino-1-(4-fluorophenyl)-4-(3-(2,3-dihydroxypropoxy)benzoyl)pyrazole?
The molecular formula of 5-Amino-1-(4-fluorophenyl)-4-(3-(2,3-dihydroxypropoxy)benzoyl)pyrazole is C19H18FN3O4.
What is the molecular weight of 5-Amino-1-(4-fluorophenyl)-4-(3-(2,3-dihydroxypropoxy)benzoyl)pyrazole?
The molecular weight of 5-Amino-1-(4-fluorophenyl)-4-(3-(2,3-dihydroxypropoxy)benzoyl)pyrazole is 371.13 g/mol.
Where can I buy 5-Amino-1-(4-fluorophenyl)-4-(3-(2,3-dihydroxypropoxy)benzoyl)pyrazole?
You can request a quote for 5-Amino-1-(4-fluorophenyl)-4-(3-(2,3-dihydroxypropoxy)benzoyl)pyrazole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-Amino-1-(4-fluorophenyl)-4-(3-(2,3-dihydroxypropoxy)benzoyl)pyrazole?
Yes, KEHONG BIO provides custom synthesis services for 5-Amino-1-(4-fluorophenyl)-4-(3-(2,3-dihydroxypropoxy)benzoyl)pyrazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.