17,21-Dihydroxy-16-methyl-9,11-epoxypregna-1,4-diene-3,20-dione
TL;DR: 17,21-Dihydroxy-16-methyl-9,11-epoxypregna-1,4-diene-3,20-dione (CAS 24916-90-3) is a chemical compound with molecular formula C22H28O5 and molecular weight 372.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
14-hydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyl-18-oxapentacyclo[8.8.0.01,17.02,7.011,15]octadeca-3,6-dien-5-one
Also Known As: Dexamethasone 9,11-Epoxide, 16-beta Methyl Epoxide, 16-, A Methyl Epoxide;, Dexamethasone EP Impurity I
| Molecular Formula | C22H28O5 |
|---|---|
| Molecular Weight | 372.19 g/mol |
| LogP | 2.0 |
| Topological Polar Surface Area | 87.1 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 372.19366 |
| Heavy Atoms | 27 |
| Complexity | 814.0 |
Chemical Identifiers
| CAS Number | 24916-90-3 |
|---|---|
| SMILES | CC1CC2C3CCC4=CC(=O)C=CC4(C35C(O5)CC2(C1(C(=O)CO)O)C)C |
| InChIKey | GBDXNHBVYAMODG-UHFFFAOYSA-N |
Product Overview
17,21-Dihydroxy-16-methyl-9,11-epoxypregna-1,4-diene-3,20-dione (CAS 24916-90-3), with molecular formula C22H28O5 and molecular weight 372.19 g/mol. IUPAC: 14-hydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyl-18-oxapentacyclo[8.8.0.01,17.02,7.011,15]octadeca-3,6-dien-5-one.
Chemical Property Profile of 17,21-Dihydroxy-16-methyl-9,11-epoxypregna-1,4-diene-3,20-dione
Property Insights of 17,21-Dihydroxy-16-methyl-9,11-epoxypregna-1,4-diene-3,20-dione
The XLogP value of 2.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 17,21-Dihydroxy-16-methyl-9,11-epoxypregna-1,4-diene-3,20-dione. The TPSA of 87.1 Ų falls within the moderate polarity range, balancing permeability and solubility for 17,21-Dihydroxy-16-methyl-9,11-epoxypregna-1,4-diene-3,20-dione. Following Lipinski's Rule of Five, 17,21-Dihydroxy-16-methyl-9,11-epoxypregna-1,4-diene-3,20-dione has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 17,21-Dihydroxy-16-methyl-9,11-epoxypregna-1,4-diene-3,20-dione?
The CAS number of 17,21-Dihydroxy-16-methyl-9,11-epoxypregna-1,4-diene-3,20-dione is 24916-90-3.
What is the molecular formula of 17,21-Dihydroxy-16-methyl-9,11-epoxypregna-1,4-diene-3,20-dione?
The molecular formula of 17,21-Dihydroxy-16-methyl-9,11-epoxypregna-1,4-diene-3,20-dione is C22H28O5.
What is the molecular weight of 17,21-Dihydroxy-16-methyl-9,11-epoxypregna-1,4-diene-3,20-dione?
The molecular weight of 17,21-Dihydroxy-16-methyl-9,11-epoxypregna-1,4-diene-3,20-dione is 372.19 g/mol.
Where can I buy 17,21-Dihydroxy-16-methyl-9,11-epoxypregna-1,4-diene-3,20-dione?
You can request a quote for 17,21-Dihydroxy-16-methyl-9,11-epoxypregna-1,4-diene-3,20-dione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 17,21-Dihydroxy-16-methyl-9,11-epoxypregna-1,4-diene-3,20-dione?
Yes, KEHONG BIO provides custom synthesis services for 17,21-Dihydroxy-16-methyl-9,11-epoxypregna-1,4-diene-3,20-dione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.