17-Hydroxy-6-dehydroprogesterone
TL;DR: 17-Hydroxy-6-dehydroprogesterone (CAS 2477-60-3) is a chemical compound with molecular formula C21H28O3 and molecular weight 328.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-10,13-dimethyl-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one
Also Known As: megestrol, 17-Hdhpg, Megestryl acetate, Megestrolo [DCIT], Progesterone Impurity 5
| Molecular Formula | C21H28O3 |
|---|---|
| Molecular Weight | 328.20 g/mol |
| LogP | 3.6144 |
| Topological Polar Surface Area | 54.37 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 328.20386 |
| Heavy Atoms | 24 |
| Complexity | 674.57135 |
Chemical Identifiers
| CAS Number | 2477-60-3 |
|---|---|
| SMILES | CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C=CC4=CC(=O)CC[C@]34C)C)O |
Product Overview
17-Hydroxy-6-dehydroprogesterone (CAS 2477-60-3), with molecular formula C21H28O3 and molecular weight 328.20 g/mol. IUPAC: (8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-10,13-dimethyl-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one.
Chemical Property Profile of 17-Hydroxy-6-dehydroprogesterone
Property Insights of 17-Hydroxy-6-dehydroprogesterone
The XLogP value of 3.6144 indicates that 17-Hydroxy-6-dehydroprogesterone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 54.37 Ų, 17-Hydroxy-6-dehydroprogesterone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 17-Hydroxy-6-dehydroprogesterone has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 17-Hydroxy-6-dehydroprogesterone?
The CAS number of 17-Hydroxy-6-dehydroprogesterone is 2477-60-3.
What is the molecular formula of 17-Hydroxy-6-dehydroprogesterone?
The molecular formula of 17-Hydroxy-6-dehydroprogesterone is C21H28O3.
What is the molecular weight of 17-Hydroxy-6-dehydroprogesterone?
The molecular weight of 17-Hydroxy-6-dehydroprogesterone is 328.20 g/mol.
Where can I buy 17-Hydroxy-6-dehydroprogesterone?
You can request a quote for 17-Hydroxy-6-dehydroprogesterone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 17-Hydroxy-6-dehydroprogesterone?
Yes, KEHONG BIO provides custom synthesis services for 17-Hydroxy-6-dehydroprogesterone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.