Spiclomazine
TL;DR: Spiclomazine (CAS 24527-27-3) is a chemical compound with molecular formula C22H24ClN3OS2 and molecular weight 445.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
8-[3-(2-chlorophenothiazin-10-yl)propyl]-1-thia-4,8-diazaspiro[4.5]decan-3-one
Also Known As: Spiclomazine, Clospirazine, Espiclomazina, Spiclomazinum, Spiclomazine [INN]
| Molecular Formula | C22H24ClN3OS2 |
|---|---|
| Molecular Weight | 445.10 g/mol |
| LogP | 5.3 |
| Topological Polar Surface Area | 86.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 445.10492 |
| Heavy Atoms | 29 |
| Complexity | 601.0 |
Chemical Identifiers
| CAS Number | 24527-27-3 |
|---|---|
| SMILES | C1CN(CCC12NC(=O)CS2)CCCN3C4=CC=CC=C4SC5=C3C=C(C=C5)Cl |
| InChIKey | CFOYBMUYCBSDAL-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 6 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Spiclomazine (CAS 24527-27-3), with molecular formula C22H24ClN3OS2 and molecular weight 445.10 g/mol. IUPAC: 8-[3-(2-chlorophenothiazin-10-yl)propyl]-1-thia-4,8-diazaspiro[4.5]decan-3-one.
Chemical Property Profile of Spiclomazine
Property Insights of Spiclomazine
The XLogP value of 5.3 indicates that Spiclomazine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 86.2 Ų falls within the moderate polarity range, balancing permeability and solubility for Spiclomazine. Following Lipinski's Rule of Five, Spiclomazine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Spiclomazine?
The CAS number of Spiclomazine is 24527-27-3.
What is the molecular formula of Spiclomazine?
The molecular formula of Spiclomazine is C22H24ClN3OS2.
What is the molecular weight of Spiclomazine?
The molecular weight of Spiclomazine is 445.10 g/mol.
Where can I buy Spiclomazine?
You can request a quote for Spiclomazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Spiclomazine?
Yes, KEHONG BIO provides custom synthesis services for Spiclomazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.