3-(5-(2-Thienyl)-1,2,4-oxadiazol-3-yl)quinolin-2-ol
TL;DR: 3-(5-(2-Thienyl)-1,2,4-oxadiazol-3-yl)quinolin-2-ol (CAS 245121-33-9) is a chemical compound with molecular formula C15H9N3O2S and molecular weight 295.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-(5-thiophen-2-yl-1,2,4-oxadiazol-3-yl)-1H-quinolin-2-one
Also Known As: BAS 08978327, 3-(5-(thiophen-2-yl)-1,2,4-oxadiazol-3-yl)quinolin-2-ol, 3-(5-(2-thienyl)-1,2,4-oxadiazol-3-yl)quinolin-2-ol, 3-(5-Thiophen-2-yl-[1,2,4]oxadiazol-3-yl)-quinolin-2-ol, 3-(5-thiophen-2-yl-1,2,4-oxadiazol-3-ylidene)quinolin-2-one
| Molecular Formula | C15H9N3O2S |
|---|---|
| Molecular Weight | 295.04 g/mol |
| LogP | 3.3066 |
| Topological Polar Surface Area | 71.78 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 295.04153 |
| Heavy Atoms | 21 |
| Complexity | 969.9289 |
Chemical Identifiers
| CAS Number | 245121-33-9 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C=C(C(=O)N2)C3=NOC(=N3)C4=CC=CS4 |
Product Overview
3-(5-(2-Thienyl)-1,2,4-oxadiazol-3-yl)quinolin-2-ol (CAS 245121-33-9), with molecular formula C15H9N3O2S and molecular weight 295.04 g/mol. IUPAC: 3-(5-thiophen-2-yl-1,2,4-oxadiazol-3-yl)-1H-quinolin-2-one.
Chemical Property Profile of 3-(5-(2-Thienyl)-1,2,4-oxadiazol-3-yl)quinolin-2-ol
Property Insights of 3-(5-(2-Thienyl)-1,2,4-oxadiazol-3-yl)quinolin-2-ol
The XLogP value of 3.3066 indicates that 3-(5-(2-Thienyl)-1,2,4-oxadiazol-3-yl)quinolin-2-ol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 71.78 Ų falls within the moderate polarity range, balancing permeability and solubility for 3-(5-(2-Thienyl)-1,2,4-oxadiazol-3-yl)quinolin-2-ol. Following Lipinski's Rule of Five, 3-(5-(2-Thienyl)-1,2,4-oxadiazol-3-yl)quinolin-2-ol has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-(5-(2-Thienyl)-1,2,4-oxadiazol-3-yl)quinolin-2-ol?
The CAS number of 3-(5-(2-Thienyl)-1,2,4-oxadiazol-3-yl)quinolin-2-ol is 245121-33-9.
What is the molecular formula of 3-(5-(2-Thienyl)-1,2,4-oxadiazol-3-yl)quinolin-2-ol?
The molecular formula of 3-(5-(2-Thienyl)-1,2,4-oxadiazol-3-yl)quinolin-2-ol is C15H9N3O2S.
What is the molecular weight of 3-(5-(2-Thienyl)-1,2,4-oxadiazol-3-yl)quinolin-2-ol?
The molecular weight of 3-(5-(2-Thienyl)-1,2,4-oxadiazol-3-yl)quinolin-2-ol is 295.04 g/mol.
Where can I buy 3-(5-(2-Thienyl)-1,2,4-oxadiazol-3-yl)quinolin-2-ol?
You can request a quote for 3-(5-(2-Thienyl)-1,2,4-oxadiazol-3-yl)quinolin-2-ol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-(5-(2-Thienyl)-1,2,4-oxadiazol-3-yl)quinolin-2-ol?
Yes, KEHONG BIO provides custom synthesis services for 3-(5-(2-Thienyl)-1,2,4-oxadiazol-3-yl)quinolin-2-ol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.