Lidorestat
TL;DR: Lidorestat (CAS 245117-13-9) is a chemical compound with molecular formula C18H11F3N2O2S and molecular weight 376.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[3-[(4,5,7-trifluoro-1,3-benzothiazol-2-yl)methyl]indol-1-yl]acetic acid
Also Known As: Lidorestat, Lindolrestat, Lindorestat, Lidorestat anhydrous, Lidorestat [USAN]
| Molecular Formula | C18H11F3N2O2S |
|---|---|
| Molecular Weight | 376.05 g/mol |
| LogP | 4.4 |
| Topological Polar Surface Area | 83.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 4 |
| Exact Mass | 376.04935 |
| Heavy Atoms | 26 |
| Complexity | 543.0 |
Chemical Identifiers
| CAS Number | 245117-13-9 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C(=CN2CC(=O)O)CC3=NC4=C(C(=CC(=C4S3)F)F)F |
| InChIKey | KYHVTMFADJNSGS-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Lidorestat (CAS 245117-13-9), with molecular formula C18H11F3N2O2S and molecular weight 376.05 g/mol. IUPAC: 2-[3-[(4,5,7-trifluoro-1,3-benzothiazol-2-yl)methyl]indol-1-yl]acetic acid.
Chemical Property Profile of Lidorestat
Property Insights of Lidorestat
The XLogP value of 4.4 indicates that Lidorestat is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 83.4 Ų falls within the moderate polarity range, balancing permeability and solubility for Lidorestat. Following Lipinski's Rule of Five, Lidorestat has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Lidorestat?
The CAS number of Lidorestat is 245117-13-9.
What is the molecular formula of Lidorestat?
The molecular formula of Lidorestat is C18H11F3N2O2S.
What is the molecular weight of Lidorestat?
The molecular weight of Lidorestat is 376.05 g/mol.
Where can I buy Lidorestat?
You can request a quote for Lidorestat directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Lidorestat?
Yes, KEHONG BIO provides custom synthesis services for Lidorestat and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.