Leupeptin structure

Leupeptin

TL;DR: Leupeptin (CAS 24365-47-7) is a chemical compound with molecular formula C20H38N6O4 and molecular weight 426.30 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2S)-2-acetamido-N-[1-[[5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-methylpentanamide

Also Known As: Leupeptin, Leupeptin Ac-LL, Leupeptin hemisulfate salt, Acetyl-L-leucyl-L-leucylargininal, N-Acetyl-L-leucyl-L-leucyl-L-argininal

CAS: 24365-47-7
Molecular Formula C20H38N6O4
Molecular Weight 426.30 g/mol
LogP 0.4
Topological Polar Surface Area 169.0 Ų
Hydrogen Bond Donors 5
Hydrogen Bond Acceptors 5
Rotatable Bonds 14
Exact Mass 426.29544
Heavy Atoms 30
Complexity 602.0

Chemical Identifiers

CAS Number 24365-47-7
SMILES CC(C)C[C@@H](C(=O)NC(CC(C)C)C(=O)NC(CCCN=C(N)N)C=O)NC(=O)C
InChIKey GDBQQVLCIARPGH-CGZBRXJRSA-N

Product Overview

Leupeptin (CAS 24365-47-7), with molecular formula C20H38N6O4 and molecular weight 426.30 g/mol. IUPAC: (2S)-2-acetamido-N-[1-[[5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-methylpentanamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Leupeptin

XLogP
0.4
TPSA (Topological Polar Surface Area)
169.0
Hydrogen Bond Donors
5
Hydrogen Bond Acceptors
5
Rotatable Bonds
14
Heavy Atoms
30
Complexity
602.0
Exact Mass
426.29544
Monoisotopic Mass
426.29544
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Leupeptin

The XLogP value of 0.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Leupeptin. The TPSA of 169.0 Ų indicates high polarity, suggesting Leupeptin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Leupeptin has 5 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Leupeptin?

The CAS number of Leupeptin is 24365-47-7.

What is the molecular formula of Leupeptin?

The molecular formula of Leupeptin is C20H38N6O4.

What is the molecular weight of Leupeptin?

The molecular weight of Leupeptin is 426.30 g/mol.

Where can I buy Leupeptin?

You can request a quote for Leupeptin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Leupeptin?

Yes, KEHONG BIO provides custom synthesis services for Leupeptin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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