Nivazol
TL;DR: Nivazol (CAS 24358-76-7) is a chemical compound with molecular formula C28H31FN2O and molecular weight 430.24 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(1S,2R,13R,14S,17R,18S)-17-ethynyl-7-(4-fluorophenyl)-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-ol
Also Known As: Nivacortol, NIVAZOL, Nivacortolum, Nivazol [USAN], Nivacortol [INN]
| Molecular Formula | C28H31FN2O |
|---|---|
| Molecular Weight | 430.24 g/mol |
| LogP | 5.5578 |
| Topological Polar Surface Area | 38.05 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 430.24203 |
| Heavy Atoms | 32 |
| Complexity | 1157.0853 |
Chemical Identifiers
| CAS Number | 24358-76-7 |
|---|---|
| SMILES | C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=CC5=C(C[C@]34C)C=NN5C6=CC=C(C=C6)F |
Product Overview
Nivazol (CAS 24358-76-7), with molecular formula C28H31FN2O and molecular weight 430.24 g/mol. IUPAC: (1S,2R,13R,14S,17R,18S)-17-ethynyl-7-(4-fluorophenyl)-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-ol.
Chemical Property Profile of Nivazol
Property Insights of Nivazol
The XLogP value of 5.5578 indicates that Nivazol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 38.05 Ų, Nivazol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Nivazol has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Nivazol?
The CAS number of Nivazol is 24358-76-7.
What is the molecular formula of Nivazol?
The molecular formula of Nivazol is C28H31FN2O.
What is the molecular weight of Nivazol?
The molecular weight of Nivazol is 430.24 g/mol.
Where can I buy Nivazol?
You can request a quote for Nivazol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Nivazol?
Yes, KEHONG BIO provides custom synthesis services for Nivazol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.