Berberastine structure

Berberastine

TL;DR: Berberastine (CAS 2435-73-6) is a chemical compound with molecular formula C20H18NO5+ and molecular weight 352.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

16,17-dimethoxy-5,7-dioxa-13-azoniapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(13),2,4(8),9,14,16,18,20-octaen-11-ol

Also Known As: Berberastine, Berberine Impurity 3, Benzo(g)-1,3-benzodioxolo(5,6-a)quinolizinium, 5,6-dihydro-5-hydroxy-9,10-dimethoxy-, 16,17-dimethoxy-5,7-dioxa-13-azoniapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(13),2,4(8),9,14,16,18,20-octaen-11-ol, 5,6-Dihydro-5-hydroxy-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium

CAS: 2435-73-6
Molecular Formula C20H18NO5+
Molecular Weight 352.12 g/mol
LogP 2.5
Topological Polar Surface Area 61.0 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 5
Rotatable Bonds 2
Exact Mass 352.1185
Heavy Atoms 26
Complexity 518.0

Chemical Identifiers

CAS Number 2435-73-6
SMILES COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC5=C(C=C4C(C3)O)OCO5)OC
InChIKey VFCGRXCCUHLLIP-UHFFFAOYSA-N

Product Overview

Berberastine (CAS 2435-73-6), with molecular formula C20H18NO5+ and molecular weight 352.12 g/mol. IUPAC: 16,17-dimethoxy-5,7-dioxa-13-azoniapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(13),2,4(8),9,14,16,18,20-octaen-11-ol.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Berberastine

XLogP
2.5
TPSA (Topological Polar Surface Area)
61.0
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
5
Rotatable Bonds
2
Heavy Atoms
26
Complexity
518.0
Exact Mass
352.1185
Monoisotopic Mass
352.1185
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Berberastine

The XLogP value of 2.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Berberastine. The TPSA of 61.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Berberastine. Following Lipinski's Rule of Five, Berberastine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Berberastine?

The CAS number of Berberastine is 2435-73-6.

What is the molecular formula of Berberastine?

The molecular formula of Berberastine is C20H18NO5+.

What is the molecular weight of Berberastine?

The molecular weight of Berberastine is 352.12 g/mol.

Where can I buy Berberastine?

You can request a quote for Berberastine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Berberastine?

Yes, KEHONG BIO provides custom synthesis services for Berberastine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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