10E-335S
TL;DR: 10E-335S (CAS 242797-41-7) is a chemical compound with molecular formula C20H15ClF2N2O2 and molecular weight 388.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(3-chloro-2-methylphenyl)-1-[(3,4-difluorophenyl)methyl]-6-oxopyridine-3-carboxamide
Also Known As: 10E-335S, N-(3-chloro-2-methylphenyl)-1-(3,4-difluorobenzyl)-6-oxo-1,6-dihydro-3-pyridinecarboxamide, N-(3-chloro-2-methylphenyl)-1-[(3,4-difluorophenyl)methyl]-6-oxopyridine-3-carboxamide, N-(3-chloro-2-methylphenyl)-1-[(3,4-difluorophenyl)methyl]-6-oxo-1,6-dihydropyridine-3-carboxamide
| Molecular Formula | C20H15ClF2N2O2 |
|---|---|
| Molecular Weight | 388.08 g/mol |
| LogP | 4.38892 |
| Topological Polar Surface Area | 51.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 4 |
| Exact Mass | 388.079 |
| Heavy Atoms | 27 |
| Complexity | 1079.8171 |
Chemical Identifiers
| CAS Number | 242797-41-7 |
|---|---|
| SMILES | CC1=C(C=CC=C1Cl)NC(=O)C2=CN(C(=O)C=C2)CC3=CC(=C(C=C3)F)F |
Product Overview
10E-335S (CAS 242797-41-7), with molecular formula C20H15ClF2N2O2 and molecular weight 388.08 g/mol. IUPAC: N-(3-chloro-2-methylphenyl)-1-[(3,4-difluorophenyl)methyl]-6-oxopyridine-3-carboxamide.
Chemical Property Profile of 10E-335S
Property Insights of 10E-335S
The XLogP value of 4.38892 indicates that 10E-335S is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.1 Ų, 10E-335S exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 10E-335S has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 10E-335S?
The CAS number of 10E-335S is 242797-41-7.
What is the molecular formula of 10E-335S?
The molecular formula of 10E-335S is C20H15ClF2N2O2.
What is the molecular weight of 10E-335S?
The molecular weight of 10E-335S is 388.08 g/mol.
Where can I buy 10E-335S?
You can request a quote for 10E-335S directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 10E-335S?
Yes, KEHONG BIO provides custom synthesis services for 10E-335S and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.