10B-135
TL;DR: 10B-135 (CAS 241127-06-0) is a chemical compound with molecular formula C22H12F6N2O3 and molecular weight 466.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-oxo-2-(trifluoromethyl)-N-[[3-(trifluoromethyl)phenyl]methyl]chromeno[2,3-b]pyridine-3-carboxamide
Also Known As: 10B-135, 5-oxo-2-(trifluoromethyl)-N-[3-(trifluoromethyl)benzyl]-5H-chromeno[2,3-b]pyridine-3-carboxamide, 5-oxo-2-(trifluoromethyl)-N-[[3-(trifluoromethyl)phenyl]methyl]chromeno[2,3-b]pyridine-3-carboxamide, 5-oxo-2-(trifluoromethyl)-N-{[3-(trifluoromethyl)phenyl]methyl}-5H-chromeno[2,3-b]pyridine-3-carboxamide
| Molecular Formula | C22H12F6N2O3 |
|---|---|
| Molecular Weight | 466.08 g/mol |
| LogP | 5.3088 |
| Topological Polar Surface Area | 72.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 466.07523 |
| Heavy Atoms | 33 |
| Complexity | 1440.5248 |
Chemical Identifiers
| CAS Number | 241127-06-0 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C(=O)C3=CC(=C(N=C3O2)C(F)(F)F)C(=O)NCC4=CC(=CC=C4)C(F)(F)F |
Product Overview
10B-135 (CAS 241127-06-0), with molecular formula C22H12F6N2O3 and molecular weight 466.08 g/mol. IUPAC: 5-oxo-2-(trifluoromethyl)-N-[[3-(trifluoromethyl)phenyl]methyl]chromeno[2,3-b]pyridine-3-carboxamide.
Chemical Property Profile of 10B-135
Property Insights of 10B-135
The XLogP value of 5.3088 indicates that 10B-135 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 72.2 Ų falls within the moderate polarity range, balancing permeability and solubility for 10B-135. Following Lipinski's Rule of Five, 10B-135 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 10B-135?
The CAS number of 10B-135 is 241127-06-0.
What is the molecular formula of 10B-135?
The molecular formula of 10B-135 is C22H12F6N2O3.
What is the molecular weight of 10B-135?
The molecular weight of 10B-135 is 466.08 g/mol.
Where can I buy 10B-135?
You can request a quote for 10B-135 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 10B-135?
Yes, KEHONG BIO provides custom synthesis services for 10B-135 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.