Griffithinam
TL;DR: Griffithinam (CAS 240122-32-1) is a chemical compound with molecular formula C17H13NO4 and molecular weight 295.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
15-hydroxy-6,14-dimethoxy-10-azatetracyclo[7.6.1.02,7.012,16]hexadeca-1,3,5,7,9(16),12,14-heptaen-11-one
Also Known As: Griffithinam, Uvarilactam, Gonioffithine, J1.134.084I, 1-Hydroxy-2,7-dimethoxydibenz[cd,f]indol-4(5H)-one
| Molecular Formula | C17H13NO4 |
|---|---|
| Molecular Weight | 295.08 g/mol |
| LogP | 3.2815 |
| Topological Polar Surface Area | 67.79 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 295.08447 |
| Heavy Atoms | 22 |
| Complexity | 962.1735 |
Chemical Identifiers
| CAS Number | 240122-32-1 |
|---|---|
| SMILES | COC1=CC=CC2=C3C4=C(C=C21)NC(=O)C4=CC(=C3O)OC |
Product Overview
Griffithinam (CAS 240122-32-1), with molecular formula C17H13NO4 and molecular weight 295.08 g/mol. IUPAC: 15-hydroxy-6,14-dimethoxy-10-azatetracyclo[7.6.1.02,7.012,16]hexadeca-1,3,5,7,9(16),12,14-heptaen-11-one.
Chemical Property Profile of Griffithinam
Property Insights of Griffithinam
The XLogP value of 3.2815 indicates that Griffithinam is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 67.79 Ų falls within the moderate polarity range, balancing permeability and solubility for Griffithinam. Following Lipinski's Rule of Five, Griffithinam has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Griffithinam?
The CAS number of Griffithinam is 240122-32-1.
What is the molecular formula of Griffithinam?
The molecular formula of Griffithinam is C17H13NO4.
What is the molecular weight of Griffithinam?
The molecular weight of Griffithinam is 295.08 g/mol.
Where can I buy Griffithinam?
You can request a quote for Griffithinam directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Griffithinam?
Yes, KEHONG BIO provides custom synthesis services for Griffithinam and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.