托司多他
TL;DR: 托司多他 (CAS 238750-77-1) is a chemical compound with molecular formula C22H30N4O6S and molecular weight 478.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
托司多他
N-[2-[2-[2-[(2-amino-3-phenylpropanoyl)amino]ethoxy]ethoxy]ethyl]-4-sulfamoylbenzamide
Also Known As: Tosedostat (CHR2797), 2-amino-3-phenyl-N-[2-(2-{2-[(4-sulfamoylphenyl)formamido]ethoxy}ethoxy)ethyl]propanamide, 4-Sulfamoyl-N-[2-[2-[2-[(1-oxo-2-amino-3-phenylpropyl)amino]ethoxy]ethoxy]ethyl]benzamide, N-[2-[2-[2-[(2-amino-3-phenylpropanoyl)amino]ethoxy]ethoxy]ethyl]-4-sulfamoylbenzamide, (S)-cyclopentyl 2-((R)-2-((S)-1-hydroxy-2-(hydroxyamino)-2-oxoethyl)-4-methylpentanamido)-2-phenylacetate
| Molecular Formula | C22H30N4O6S |
|---|---|
| Molecular Weight | 478.19 g/mol |
| LogP | -0.1 |
| Topological Polar Surface Area | 171.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 14 |
| Exact Mass | 478.1886 |
| Heavy Atoms | 33 |
| Complexity | 685.0 |
Chemical Identifiers
| CAS Number | 238750-77-1 |
|---|---|
| SMILES | C1=CC=C(C=C1)CC(C(=O)NCCOCCOCCNC(=O)C2=CC=C(C=C2)S(=O)(=O)N)N |
| InChIKey | QNZDHHNWUXIYOH-UHFFFAOYSA-N |
Product Overview
托司多他 (CAS 238750-77-1), with molecular formula C22H30N4O6S and molecular weight 478.19 g/mol. IUPAC: N-[2-[2-[2-[(2-amino-3-phenylpropanoyl)amino]ethoxy]ethoxy]ethyl]-4-sulfamoylbenzamide.
Chemical Property Profile of 托司多他
Property Insights of 托司多他
The XLogP value of -0.1 indicates that 托司多他 is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 171.0 Ų indicates high polarity, suggesting 托司多他 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 托司多他 has 4 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 托司多他?
The CAS number of 托司多他 is 238750-77-1.
What is the molecular formula of 托司多他?
The molecular formula of 托司多他 is C22H30N4O6S.
What is the molecular weight of 托司多他?
The molecular weight of 托司多他 is 478.19 g/mol.
Where can I buy 托司多他?
You can request a quote for 托司多他 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 托司多他?
Yes, KEHONG BIO provides custom synthesis services for 托司多他 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.