Leurosine
TL;DR: Leurosine (CAS 23360-92-1) is a chemical compound with molecular formula C46H56N4O9 and molecular weight 808.40 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
methyl (13S,15S,16R,18S)-13-[(1R,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-10-hydroxy-5-methoxy-10-methoxycarbonyl-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraen-4-yl]-18-ethyl-17-oxa-1,11-diazapentacyclo[13.4.1.04,12.05,10.016,18]icosa-4(12),5,7,9-tetraene-13-carboxylate
Also Known As: Vinleurosine, LEUROSINE, Vinleurosina, Vinleurosinum, Amotin
| Molecular Formula | C46H56N4O9 |
|---|---|
| Molecular Weight | 808.40 g/mol |
| LogP | 3.7 |
| Topological Polar Surface Area | 146.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 12 |
| Rotatable Bonds | 10 |
| Exact Mass | 808.4047 |
| Heavy Atoms | 59 |
| Complexity | 1750.0 |
Chemical Identifiers
| CAS Number | 23360-92-1 |
|---|---|
| SMILES | CC[C@]12CN3CCC4=C([C@](C[C@@H](C3)[C@H]1O2)(C5=C(C=C6C(=C5)[C@]78CCN9[C@H]7[C@@](C=CC9)([C@H]([C@@]([C@@H]8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)NC1=CC=CC=C41 |
| InChIKey | LPGWZGMPDKDHEP-NVDFJPPOSA-N |
Product Overview
Leurosine (CAS 23360-92-1), with molecular formula C46H56N4O9 and molecular weight 808.40 g/mol. IUPAC: methyl (13S,15S,16R,18S)-13-[(1R,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-10-hydroxy-5-methoxy-10-methoxycarbonyl-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraen-4-yl]-18-ethyl-17-oxa-1,11-diazapentacyclo[13.4.1.04,12.05,10.016,18]icosa-4(12),5,7,9-tetraene-13-carboxylate.
Chemical Property Profile of Leurosine
Property Insights of Leurosine
The XLogP value of 3.7 indicates that Leurosine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 146.0 Ų indicates high polarity, suggesting Leurosine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Leurosine has 2 hydrogen bond donor(s) and 12 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Leurosine?
The CAS number of Leurosine is 23360-92-1.
What is the molecular formula of Leurosine?
The molecular formula of Leurosine is C46H56N4O9.
What is the molecular weight of Leurosine?
The molecular weight of Leurosine is 808.40 g/mol.
Where can I buy Leurosine?
You can request a quote for Leurosine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Leurosine?
Yes, KEHONG BIO provides custom synthesis services for Leurosine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.