Estradiol Mustard structure

Estradiol Mustard

TL;DR: Estradiol Mustard (CAS 22966-79-6) is a chemical compound with molecular formula C42H50Cl4N2O4 and molecular weight 786.25 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[(8R,9S,13S,14S,17S)-3-[2-[4-[bis(2-chloroethyl)amino]phenyl]acetyl]oxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] 2-[4-[bis(2-chloroethyl)amino]phenyl]acetate

Also Known As: Estradiol mustard, Oestradiol mustard, Estradiolmustard, NCI-C01570, ESTRADIOL 3,17-MUSTARD

CAS: 22966-79-6
Molecular Formula C42H50Cl4N2O4
Molecular Weight 786.25 g/mol
LogP 9.2
Topological Polar Surface Area 59.1 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 6
Rotatable Bonds 18
Exact Mass 788.2495
Heavy Atoms 52
Complexity 1120.0
Melting Point 104 to 65.0 °C (freeze dried)
Solubility Insoluble (NTP, 1992)

Chemical Identifiers

CAS Number 22966-79-6
SMILES C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2OC(=O)CC4=CC=C(C=C4)N(CCCl)CCCl)CCC5=C3C=CC(=C5)OC(=O)CC6=CC=C(C=C6)N(CCCl)CCCl
InChIKey LRSFXIJGHRPOQQ-VZRQQIPSSA-N

Product Overview

Estradiol Mustard (CAS 22966-79-6), with molecular formula C42H50Cl4N2O4 and molecular weight 786.25 g/mol. IUPAC: [(8R,9S,13S,14S,17S)-3-[2-[4-[bis(2-chloroethyl)amino]phenyl]acetyl]oxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] 2-[4-[bis(2-chloroethyl)amino]phenyl]acetate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Estradiol Mustard

XLogP
9.2
TPSA (Topological Polar Surface Area)
59.1
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
6
Rotatable Bonds
18
Heavy Atoms
52
Complexity
1120.0
Exact Mass
788.2495
Monoisotopic Mass
786.25244
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Estradiol Mustard

The XLogP value of 9.2 indicates that Estradiol Mustard is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.1 Ų, Estradiol Mustard exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Estradiol Mustard has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Estradiol Mustard?

The CAS number of Estradiol Mustard is 22966-79-6.

What is the molecular formula of Estradiol Mustard?

The molecular formula of Estradiol Mustard is C42H50Cl4N2O4.

What is the molecular weight of Estradiol Mustard?

The molecular weight of Estradiol Mustard is 786.25 g/mol.

Where can I buy Estradiol Mustard?

You can request a quote for Estradiol Mustard directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Estradiol Mustard?

Yes, KEHONG BIO provides custom synthesis services for Estradiol Mustard and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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