(-)-Didesmethylsibutramine
TL;DR: (-)-Didesmethylsibutramine (CAS 229639-57-0) is a chemical compound with molecular formula C15H22ClN and molecular weight 251.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(1S)-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutan-1-amine
Also Known As: (S)-Didesmethylsibutramine, (-)-Didesmethylsibutramine, S-(-)-Di-desmethylsibutramine, Didesmethylsibutramine, (S)-, N-Didesmethylsibutramine
| Molecular Formula | C15H22ClN |
|---|---|
| Molecular Weight | 251.14 g/mol |
| LogP | 4.1351 |
| Topological Polar Surface Area | 26.02 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 4 |
| Exact Mass | 251.14407 |
| Heavy Atoms | 17 |
| Complexity | 365.01315 |
Chemical Identifiers
| CAS Number | 229639-57-0 |
|---|---|
| SMILES | CC(C)C[C@@H](C1(CCC1)C2=CC=C(C=C2)Cl)N |
Product Overview
(-)-Didesmethylsibutramine (CAS 229639-57-0), with molecular formula C15H22ClN and molecular weight 251.14 g/mol. IUPAC: (1S)-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutan-1-amine.
Chemical Property Profile of (-)-Didesmethylsibutramine
Property Insights of (-)-Didesmethylsibutramine
The XLogP value of 4.1351 indicates that (-)-Didesmethylsibutramine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 26.02 Ų, (-)-Didesmethylsibutramine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (-)-Didesmethylsibutramine has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (-)-Didesmethylsibutramine?
The CAS number of (-)-Didesmethylsibutramine is 229639-57-0.
What is the molecular formula of (-)-Didesmethylsibutramine?
The molecular formula of (-)-Didesmethylsibutramine is C15H22ClN.
What is the molecular weight of (-)-Didesmethylsibutramine?
The molecular weight of (-)-Didesmethylsibutramine is 251.14 g/mol.
Where can I buy (-)-Didesmethylsibutramine?
You can request a quote for (-)-Didesmethylsibutramine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (-)-Didesmethylsibutramine?
Yes, KEHONG BIO provides custom synthesis services for (-)-Didesmethylsibutramine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.