R-(+)-Mono-desmethylsibutramine
TL;DR: R-(+)-Mono-desmethylsibutramine (CAS 229639-54-7) is a chemical compound with molecular formula C16H24ClN and molecular weight 265.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(1R)-1-[1-(4-chlorophenyl)cyclobutyl]-N,3-dimethylbutan-1-amine
Also Known As: R-(+)-Mono-desmethylsibutramine, (R)-Desmethylsibutramine, Desmethylsibutramine, (R)-, (R)-N,N-Desmethylsibutramine, (R)-(+)-Desmethylsibutramine
| Molecular Formula | C16H24ClN |
|---|---|
| Molecular Weight | 265.16 g/mol |
| LogP | 4.3958 |
| Topological Polar Surface Area | 12.03 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 5 |
| Exact Mass | 265.15973 |
| Heavy Atoms | 18 |
| Complexity | 378.58835 |
Chemical Identifiers
| CAS Number | 229639-54-7 |
|---|---|
| SMILES | CC(C)C[C@H](C1(CCC1)C2=CC=C(C=C2)Cl)NC |
Product Overview
R-(+)-Mono-desmethylsibutramine (CAS 229639-54-7), with molecular formula C16H24ClN and molecular weight 265.16 g/mol. IUPAC: (1R)-1-[1-(4-chlorophenyl)cyclobutyl]-N,3-dimethylbutan-1-amine.
Chemical Property Profile of R-(+)-Mono-desmethylsibutramine
Property Insights of R-(+)-Mono-desmethylsibutramine
The XLogP value of 4.3958 indicates that R-(+)-Mono-desmethylsibutramine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 12.03 Ų, R-(+)-Mono-desmethylsibutramine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, R-(+)-Mono-desmethylsibutramine has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of R-(+)-Mono-desmethylsibutramine?
The CAS number of R-(+)-Mono-desmethylsibutramine is 229639-54-7.
What is the molecular formula of R-(+)-Mono-desmethylsibutramine?
The molecular formula of R-(+)-Mono-desmethylsibutramine is C16H24ClN.
What is the molecular weight of R-(+)-Mono-desmethylsibutramine?
The molecular weight of R-(+)-Mono-desmethylsibutramine is 265.16 g/mol.
Where can I buy R-(+)-Mono-desmethylsibutramine?
You can request a quote for R-(+)-Mono-desmethylsibutramine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for R-(+)-Mono-desmethylsibutramine?
Yes, KEHONG BIO provides custom synthesis services for R-(+)-Mono-desmethylsibutramine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.