norethindrone structure

norethindrone

TL;DR: norethindrone (CAS 22933-71-7) is a chemical compound with molecular formula C20H26O2 and molecular weight 298.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(10R,13S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one

Also Known As: norethindrone, Norethisterone, Spectrum2_001066, Spectrum3_000521, Spectrum4_000079

CAS: 22933-71-7
Molecular Formula C20H26O2
Molecular Weight 298.19 g/mol
LogP 3.4925
Topological Polar Surface Area 37.3 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 2
Rotatable Bonds 0
Exact Mass 298.19327
Heavy Atoms 22
Complexity 583.0049

Chemical Identifiers

CAS Number 22933-71-7
SMILES C[C@]12CCC3[C@H]4CCC(=O)C=C4CCC3C1CC[C@]2(C#C)O

Product Overview

norethindrone (CAS 22933-71-7), with molecular formula C20H26O2 and molecular weight 298.19 g/mol. IUPAC: (10R,13S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of norethindrone

XLogP
3.4925
TPSA (Topological Polar Surface Area)
37.3
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
2
Rotatable Bonds
0
Heavy Atoms
22
Complexity
583.0049
Exact Mass
298.19327
Monoisotopic Mass
298.19327
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of norethindrone

The XLogP value of 3.4925 indicates that norethindrone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 37.3 Ų, norethindrone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, norethindrone has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of norethindrone?

The CAS number of norethindrone is 22933-71-7.

What is the molecular formula of norethindrone?

The molecular formula of norethindrone is C20H26O2.

What is the molecular weight of norethindrone?

The molecular weight of norethindrone is 298.19 g/mol.

Where can I buy norethindrone?

You can request a quote for norethindrone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for norethindrone?

Yes, KEHONG BIO provides custom synthesis services for norethindrone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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