OSI 461
TL;DR: OSI 461 (CAS 227619-96-7) is a chemical compound with molecular formula C25H22ClFN2O and molecular weight 420.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-benzyl-2-[6-fluoro-2-methyl-3-(pyridin-4-ylmethylidene)inden-1-yl]acetamide;hydrochloride
Also Known As: OSI 461, CP 461, (5-fluoro-2-methyl-1-(4-pyridyl)methylene-3-(N-benzyl)-indene)-acetamide hydrochloride, N-benzyl-2-[6-fluoro-2-methyl-3-(pyridin-4-ylmethylidene)inden-1-yl]acetamide;hydrochloride, N-benzyl-2-[(3Z)-6-fluoro-2-methyl-3-(pyridin-4-ylmethylidene)inden-1-yl]acetamide hydrochloride
| Molecular Formula | C25H22ClFN2O |
|---|---|
| Molecular Weight | 420.14 g/mol |
| LogP | 5.6767 |
| Topological Polar Surface Area | 42.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 420.14047 |
| Heavy Atoms | 30 |
| Complexity | 643.0 |
Chemical Identifiers
| CAS Number | 227619-96-7 |
|---|---|
| SMILES | CC1=C(C2=C(C1=CC3=CC=NC=C3)C=CC(=C2)F)CC(=O)NCC4=CC=CC=C4.Cl |
| InChIKey | KGXPDNOBLLACKL-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
OSI 461 (CAS 227619-96-7), with molecular formula C25H22ClFN2O and molecular weight 420.14 g/mol. IUPAC: N-benzyl-2-[6-fluoro-2-methyl-3-(pyridin-4-ylmethylidene)inden-1-yl]acetamide;hydrochloride.
Chemical Property Profile of OSI 461
Property Insights of OSI 461
The XLogP value of 5.6767 indicates that OSI 461 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 42.0 Ų, OSI 461 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, OSI 461 has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of OSI 461?
The CAS number of OSI 461 is 227619-96-7.
What is the molecular formula of OSI 461?
The molecular formula of OSI 461 is C25H22ClFN2O.
What is the molecular weight of OSI 461?
The molecular weight of OSI 461 is 420.14 g/mol.
Where can I buy OSI 461?
You can request a quote for OSI 461 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for OSI 461?
Yes, KEHONG BIO provides custom synthesis services for OSI 461 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.