CP-461 free base
TL;DR: CP-461 free base (CAS 227619-92-3) is a chemical compound with molecular formula C25H21FN2O and molecular weight 384.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-benzyl-2-[(3Z)-6-fluoro-2-methyl-3-(pyridin-4-ylmethylidene)inden-1-yl]acetamide
Also Known As: CP-461 free base, OSI-461 free base, CP 461 (free base), 227619-92-3 (free base), 1H-Indene-3-acetamide, 5-fluoro-2-methyl-N-(phenylmethyl)-1-(4-pyridinylmethylene)-, (1Z)-
| Molecular Formula | C25H21FN2O |
|---|---|
| Molecular Weight | 384.16 g/mol |
| LogP | 5.2549 |
| Topological Polar Surface Area | 41.99 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 5 |
| Exact Mass | 384.1638 |
| Heavy Atoms | 29 |
| Complexity | 1102.182 |
Chemical Identifiers
| CAS Number | 227619-92-3 |
|---|---|
| SMILES | CC\1=C(C2=C(/C1=C\C3=CC=NC=C3)C=CC(=C2)F)CC(=O)NCC4=CC=CC=C4 |
Product Overview
CP-461 free base (CAS 227619-92-3), with molecular formula C25H21FN2O and molecular weight 384.16 g/mol. IUPAC: N-benzyl-2-[(3Z)-6-fluoro-2-methyl-3-(pyridin-4-ylmethylidene)inden-1-yl]acetamide.
Chemical Property Profile of CP-461 free base
Property Insights of CP-461 free base
The XLogP value of 5.2549 indicates that CP-461 free base is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.99 Ų, CP-461 free base exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, CP-461 free base has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of CP-461 free base?
The CAS number of CP-461 free base is 227619-92-3.
What is the molecular formula of CP-461 free base?
The molecular formula of CP-461 free base is C25H21FN2O.
What is the molecular weight of CP-461 free base?
The molecular weight of CP-461 free base is 384.16 g/mol.
Where can I buy CP-461 free base?
You can request a quote for CP-461 free base directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for CP-461 free base?
Yes, KEHONG BIO provides custom synthesis services for CP-461 free base and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.