A-278637
TL;DR: A-278637 (CAS 227609-66-7) is a chemical compound with molecular formula C17H15BrFNO3S and molecular weight 410.99 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(9S)-9-(3-bromo-4-fluorophenyl)-1,1-dioxo-3,4,5,6,7,9-hexahydro-2H-thieno[3,2-b]quinolin-8-one
Also Known As: Thieno(3,2-b)quinolin-8(4H)-one, 9-(3-bromo-4-fluorophenyl)-2,3,5,6,7,9-hexahydro-, 1,1-dioxide, (9S)-, (9S)-9-(3-bromo-4-fluorophenyl)-1,1-dioxo-3,4,5,6,7,9-hexahydro-2H-thieno[3,2-b]quinolin-8-one, (S)-9-(3-Bromo-4-fluoro-phenyl)-1,1-dioxo-1,2,3,4,5,6,7,9-octahydro-1l6-thieno[3,2-b]quinolin-8-one, 9-(3-bromo-4-fluorophenyl)-2,3,5,6,7,9-hexahydrothieno(3,2-b)quinolin-8(4H)-one 1,1-dioxide, RefChem:914832
| Molecular Formula | C17H15BrFNO3S |
|---|---|
| Molecular Weight | 410.99 g/mol |
| LogP | 3.3122 |
| Topological Polar Surface Area | 63.24 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 410.99402 |
| Heavy Atoms | 24 |
| Complexity | 933.1541 |
Chemical Identifiers
| CAS Number | 227609-66-7 |
|---|---|
| SMILES | C1CC2=C([C@@H](C3=C(N2)CCS3(=O)=O)C4=CC(=C(C=C4)F)Br)C(=O)C1 |
Product Overview
A-278637 (CAS 227609-66-7), with molecular formula C17H15BrFNO3S and molecular weight 410.99 g/mol. IUPAC: (9S)-9-(3-bromo-4-fluorophenyl)-1,1-dioxo-3,4,5,6,7,9-hexahydro-2H-thieno[3,2-b]quinolin-8-one.
Chemical Property Profile of A-278637
Property Insights of A-278637
The XLogP value of 3.3122 indicates that A-278637 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 63.24 Ų falls within the moderate polarity range, balancing permeability and solubility for A-278637. Following Lipinski's Rule of Five, A-278637 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of A-278637?
The CAS number of A-278637 is 227609-66-7.
What is the molecular formula of A-278637?
The molecular formula of A-278637 is C17H15BrFNO3S.
What is the molecular weight of A-278637?
The molecular weight of A-278637 is 410.99 g/mol.
Where can I buy A-278637?
You can request a quote for A-278637 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for A-278637?
Yes, KEHONG BIO provides custom synthesis services for A-278637 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.