Proquazone
TL;DR: Proquazone (CAS 22760-18-5) is a chemical compound with molecular formula C18H18N2O and molecular weight 278.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
7-methyl-4-phenyl-1-propan-2-ylquinazolin-2-one
Also Known As: Arthrex, Biarison, Proquazonum, Procuazona, Proquazona
| Molecular Formula | C18H18N2O |
|---|---|
| Molecular Weight | 278.14 g/mol |
| LogP | 3.0 |
| Topological Polar Surface Area | 32.7 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 2 |
| Exact Mass | 278.1419 |
| Heavy Atoms | 21 |
| Complexity | 423.0 |
Chemical Identifiers
| CAS Number | 22760-18-5 |
|---|---|
| SMILES | CC1=CC2=C(C=C1)C(=NC(=O)N2C(C)C)C3=CC=CC=C3 |
| InChIKey | JTIGKVIOEQASGT-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 12 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Proquazone (CAS 22760-18-5), with molecular formula C18H18N2O and molecular weight 278.14 g/mol. IUPAC: 7-methyl-4-phenyl-1-propan-2-ylquinazolin-2-one.
Chemical Property Profile of Proquazone
Property Insights of Proquazone
The XLogP value of 3.0 indicates that Proquazone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 32.7 Ų, Proquazone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Proquazone has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Proquazone?
The CAS number of Proquazone is 22760-18-5.
What is the molecular formula of Proquazone?
The molecular formula of Proquazone is C18H18N2O.
What is the molecular weight of Proquazone?
The molecular weight of Proquazone is 278.14 g/mol.
Where can I buy Proquazone?
You can request a quote for Proquazone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Proquazone?
Yes, KEHONG BIO provides custom synthesis services for Proquazone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.