3-Hydroxyhalazepam
TL;DR: 3-Hydroxyhalazepam (CAS 22753-75-9) is a chemical compound with molecular formula C17H12ClF3N2O2 and molecular weight 368.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
7-chloro-3-hydroxy-5-phenyl-1-(2,2,2-trifluoroethyl)-3H-1,4-benzodiazepin-2-one
Also Known As: 3-Hydroxyhalazepam, 7-chloro-3-hydroxy-5-phenyl-1-(2,2,2-trifluoroethyl)-3H-1,4-benzodiazepin-2-one, 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-3-hydroxy-5-phenyl-1-(2,2,2-trifluoroethyl)-, 2H-1,4-Benzodiazepin-2-one,7-chloro-1,3-dihydro-3-hydroxy-5-phenyl-1-(2,2,2-trifluoroethyl), 7-Chloro-1,3-dihydro-3-hydroxy-5-phenyl-1-(2,2,2-trifluoroethyl)-2H-1,4-benzodiazepin-2-one
| Molecular Formula | C17H12ClF3N2O2 |
|---|---|
| Molecular Weight | 368.05 g/mol |
| LogP | 3.4047 |
| Topological Polar Surface Area | 52.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 368.05392 |
| Heavy Atoms | 25 |
| Complexity | 837.53174 |
Chemical Identifiers
| CAS Number | 22753-75-9 |
|---|---|
| SMILES | C1=CC=C(C=C1)C2=NC(C(=O)N(C3=C2C=C(C=C3)Cl)CC(F)(F)F)O |
Product Overview
3-Hydroxyhalazepam (CAS 22753-75-9), with molecular formula C17H12ClF3N2O2 and molecular weight 368.05 g/mol. IUPAC: 7-chloro-3-hydroxy-5-phenyl-1-(2,2,2-trifluoroethyl)-3H-1,4-benzodiazepin-2-one.
Chemical Property Profile of 3-Hydroxyhalazepam
Property Insights of 3-Hydroxyhalazepam
The XLogP value of 3.4047 indicates that 3-Hydroxyhalazepam is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 52.9 Ų, 3-Hydroxyhalazepam exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-Hydroxyhalazepam has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-Hydroxyhalazepam?
The CAS number of 3-Hydroxyhalazepam is 22753-75-9.
What is the molecular formula of 3-Hydroxyhalazepam?
The molecular formula of 3-Hydroxyhalazepam is C17H12ClF3N2O2.
What is the molecular weight of 3-Hydroxyhalazepam?
The molecular weight of 3-Hydroxyhalazepam is 368.05 g/mol.
Where can I buy 3-Hydroxyhalazepam?
You can request a quote for 3-Hydroxyhalazepam directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-Hydroxyhalazepam?
Yes, KEHONG BIO provides custom synthesis services for 3-Hydroxyhalazepam and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.