Syk Inhibitor II
TL;DR: Syk Inhibitor II (CAS 227449-73-2) is a chemical compound with molecular formula C14H15F3N6O and molecular weight 340.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(2-aminoethylamino)-4-[3-(trifluoromethyl)anilino]pyrimidine-5-carboxamide
Also Known As: Syk Inhibitor II, K00592a, Spleen Tyrosine Kinase Inhibitor II, SDCCGSBI-0086713.P003, 2-((2-Aminoethyl)amino)-4-((3-(trifluoromethyl)phenyl)amino)pyrimidine-5-carboxamide
| Molecular Formula | C14H15F3N6O |
|---|---|
| Molecular Weight | 340.13 g/mol |
| LogP | 1.7085 |
| Topological Polar Surface Area | 118.95 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 340.12595 |
| Heavy Atoms | 24 |
| Complexity | 734.69 |
Chemical Identifiers
| CAS Number | 227449-73-2 |
|---|---|
| SMILES | C1=CC(=CC(=C1)NC2=NC(=NC=C2C(=O)N)NCCN)C(F)(F)F |
Product Overview
Syk Inhibitor II (CAS 227449-73-2), with molecular formula C14H15F3N6O and molecular weight 340.13 g/mol. IUPAC: 2-(2-aminoethylamino)-4-[3-(trifluoromethyl)anilino]pyrimidine-5-carboxamide.
Chemical Property Profile of Syk Inhibitor II
Property Insights of Syk Inhibitor II
The XLogP value of 1.7085 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Syk Inhibitor II. The TPSA of 118.95 Ų falls within the moderate polarity range, balancing permeability and solubility for Syk Inhibitor II. Following Lipinski's Rule of Five, Syk Inhibitor II has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Syk Inhibitor II?
The CAS number of Syk Inhibitor II is 227449-73-2.
What is the molecular formula of Syk Inhibitor II?
The molecular formula of Syk Inhibitor II is C14H15F3N6O.
What is the molecular weight of Syk Inhibitor II?
The molecular weight of Syk Inhibitor II is 340.13 g/mol.
Where can I buy Syk Inhibitor II?
You can request a quote for Syk Inhibitor II directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Syk Inhibitor II?
Yes, KEHONG BIO provides custom synthesis services for Syk Inhibitor II and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.