![(3E)-3-[[4-(4-fluorophenyl)piperazin-1-yl]methylidene]-1,2-dihydropyrrolo[2,1-b]quinazolin-9-one structure](/static/products/227/227189-25-5.png)
(3E)-3-[[4-(4-fluorophenyl)piperazin-1-yl]methylidene]-1,2-dihydropyrrolo[2,1-b]quinazolin-9-one
TL;DR: (3E)-3-[[4-(4-fluorophenyl)piperazin-1-yl]methylidene]-1,2-dihydropyrrolo[2,1-b]quinazolin-9-one (CAS 227189-25-5) is a chemical compound with molecular formula C22H21FN4O and molecular weight 376.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(3E)-3-[[4-(4-fluorophenyl)piperazin-1-yl]methylidene]-1,2-dihydropyrrolo[2,1-b]quinazolin-9-one
Also Known As: (3E)-3-[[4-(4-fluorophenyl)piperazin-1-yl]methylidene]-1,2-dihydropyrrolo[2,1-b]quinazolin-9-one, (3E)-3-{[4-(4-fluorophenyl)piperazin-1-yl]methylidene}-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one, (E)-3-((4-(4-fluorophenyl)piperazin-1-yl)methylene)-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one
| Molecular Formula | C22H21FN4O |
|---|---|
| Molecular Weight | 376.17 g/mol |
| LogP | 3.1024 |
| Topological Polar Surface Area | 41.37 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 376.16995 |
| Heavy Atoms | 28 |
| Complexity | 1111.5801 |
Chemical Identifiers
| CAS Number | 227189-25-5 |
|---|---|
| SMILES | C\1CN2C(=NC3=CC=CC=C3C2=O)/C1=C/N4CCN(CC4)C5=CC=C(C=C5)F |
Product Overview
(3E)-3-[[4-(4-fluorophenyl)piperazin-1-yl]methylidene]-1,2-dihydropyrrolo[2,1-b]quinazolin-9-one (CAS 227189-25-5), with molecular formula C22H21FN4O and molecular weight 376.17 g/mol. IUPAC: (3E)-3-[[4-(4-fluorophenyl)piperazin-1-yl]methylidene]-1,2-dihydropyrrolo[2,1-b]quinazolin-9-one.
Chemical Property Profile of (3E)-3-[[4-(4-fluorophenyl)piperazin-1-yl]methylidene]-1,2-dihydropyrrolo[2,1-b]quinazolin-9-one
Property Insights of (3E)-3-[[4-(4-fluorophenyl)piperazin-1-yl]methylidene]-1,2-dihydropyrrolo[2,1-b]quinazolin-9-one
The XLogP value of 3.1024 indicates that (3E)-3-[[4-(4-fluorophenyl)piperazin-1-yl]methylidene]-1,2-dihydropyrrolo[2,1-b]quinazolin-9-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.37 Ų, (3E)-3-[[4-(4-fluorophenyl)piperazin-1-yl]methylidene]-1,2-dihydropyrrolo[2,1-b]quinazolin-9-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (3E)-3-[[4-(4-fluorophenyl)piperazin-1-yl]methylidene]-1,2-dihydropyrrolo[2,1-b]quinazolin-9-one has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (3E)-3-[[4-(4-fluorophenyl)piperazin-1-yl]methylidene]-1,2-dihydropyrrolo[2,1-b]quinazolin-9-one?
The CAS number of (3E)-3-[[4-(4-fluorophenyl)piperazin-1-yl]methylidene]-1,2-dihydropyrrolo[2,1-b]quinazolin-9-one is 227189-25-5.
What is the molecular formula of (3E)-3-[[4-(4-fluorophenyl)piperazin-1-yl]methylidene]-1,2-dihydropyrrolo[2,1-b]quinazolin-9-one?
The molecular formula of (3E)-3-[[4-(4-fluorophenyl)piperazin-1-yl]methylidene]-1,2-dihydropyrrolo[2,1-b]quinazolin-9-one is C22H21FN4O.
What is the molecular weight of (3E)-3-[[4-(4-fluorophenyl)piperazin-1-yl]methylidene]-1,2-dihydropyrrolo[2,1-b]quinazolin-9-one?
The molecular weight of (3E)-3-[[4-(4-fluorophenyl)piperazin-1-yl]methylidene]-1,2-dihydropyrrolo[2,1-b]quinazolin-9-one is 376.17 g/mol.
Where can I buy (3E)-3-[[4-(4-fluorophenyl)piperazin-1-yl]methylidene]-1,2-dihydropyrrolo[2,1-b]quinazolin-9-one?
You can request a quote for (3E)-3-[[4-(4-fluorophenyl)piperazin-1-yl]methylidene]-1,2-dihydropyrrolo[2,1-b]quinazolin-9-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (3E)-3-[[4-(4-fluorophenyl)piperazin-1-yl]methylidene]-1,2-dihydropyrrolo[2,1-b]quinazolin-9-one?
Yes, KEHONG BIO provides custom synthesis services for (3E)-3-[[4-(4-fluorophenyl)piperazin-1-yl]methylidene]-1,2-dihydropyrrolo[2,1-b]quinazolin-9-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.