福沙那韦
TL;DR: 福沙那韦 (CAS 226700-80-7) is a chemical compound with molecular formula C25H36N3O9PS and molecular weight 585.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
福沙那韦
[(3S)-oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-1-phenyl-3-phosphonooxybutan-2-yl]carbamate
Also Known As: Fosamprenavir, Telzir, fos-amprenavir, Lexiva, FOS-APV
| Molecular Formula | C25H36N3O9PS |
|---|---|
| Molecular Weight | 585.19 g/mol |
| LogP | 1.8 |
| Topological Polar Surface Area | 186.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 11 |
| Rotatable Bonds | 14 |
| Exact Mass | 585.191 |
| Heavy Atoms | 39 |
| Complexity | 912.0 |
| Solubility | White to cream colored solid. Solubility in water is approximately 0.31 mg/mL at 25 °C /Calcium salt/ |
Chemical Identifiers
| CAS Number | 226700-80-7 |
|---|---|
| SMILES | CC(C)CN(C[C@H]([C@H](CC1=CC=CC=C1)NC(=O)O[C@H]2CCOC2)OP(=O)(O)O)S(=O)(=O)C3=CC=C(C=C3)N |
| InChIKey | MLBVMOWEQCZNCC-OEMFJLHTSA-N |
Patent-Derived Application Labels
Derived from 9 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
福沙那韦 (CAS 226700-80-7), with molecular formula C25H36N3O9PS and molecular weight 585.19 g/mol. IUPAC: [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-1-phenyl-3-phosphonooxybutan-2-yl]carbamate.
Chemical Property Profile of 福沙那韦
Property Insights of 福沙那韦
The XLogP value of 1.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 福沙那韦. The TPSA of 186.0 Ų indicates high polarity, suggesting 福沙那韦 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 福沙那韦 has 4 hydrogen bond donor(s) and 11 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 福沙那韦?
The CAS number of 福沙那韦 is 226700-80-7.
What is the molecular formula of 福沙那韦?
The molecular formula of 福沙那韦 is C25H36N3O9PS.
What is the molecular weight of 福沙那韦?
The molecular weight of 福沙那韦 is 585.19 g/mol.
Where can I buy 福沙那韦?
You can request a quote for 福沙那韦 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 福沙那韦?
Yes, KEHONG BIO provides custom synthesis services for 福沙那韦 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.