乐伐替尼
TL;DR: 乐伐替尼 (CAS 2264050-65-7) is a chemical compound with molecular formula C21H19ClN4O4 and molecular weight 426.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
乐伐替尼
4-[3-chloro-4-(cyclopropylcarbamoylamino)phenoxy]-7-methoxyquinoline-6-carboxamide
Also Known As: Lenvatinib, Lenvima, Kisplyx, Lenvatinib base, lenvatinibum
| Molecular Formula | C21H19ClN4O4 |
|---|---|
| Molecular Weight | 426.11 g/mol |
| LogP | 4.0719 |
| Topological Polar Surface Area | 115.57 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 426.1095 |
| Heavy Atoms | 30 |
| Complexity | 1147.2997 |
Chemical Identifiers
| CAS Number | 2264050-65-7 |
|---|---|
| SMILES | COC1=CC2=NC=CC(=C2C=C1C(=O)N)OC3=CC(=C(C=C3)NC(=O)NC4CC4)Cl |
Product Overview
乐伐替尼 (CAS 2264050-65-7), with molecular formula C21H19ClN4O4 and molecular weight 426.11 g/mol. IUPAC: 4-[3-chloro-4-(cyclopropylcarbamoylamino)phenoxy]-7-methoxyquinoline-6-carboxamide.
Chemical Property Profile of 乐伐替尼
Property Insights of 乐伐替尼
The XLogP value of 4.0719 indicates that 乐伐替尼 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 115.57 Ų falls within the moderate polarity range, balancing permeability and solubility for 乐伐替尼. Following Lipinski's Rule of Five, 乐伐替尼 has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 乐伐替尼?
The CAS number of 乐伐替尼 is 2264050-65-7.
What is the molecular formula of 乐伐替尼?
The molecular formula of 乐伐替尼 is C21H19ClN4O4.
What is the molecular weight of 乐伐替尼?
The molecular weight of 乐伐替尼 is 426.11 g/mol.
Where can I buy 乐伐替尼?
You can request a quote for 乐伐替尼 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 乐伐替尼?
Yes, KEHONG BIO provides custom synthesis services for 乐伐替尼 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.