6alpha-Hydroxycortisol
TL;DR: 6alpha-Hydroxycortisol (CAS 22561-27-9) is a chemical compound with molecular formula C21H30O6 and molecular weight 378.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(6S,8S,9S,10R,11S,13S,14S,17R)-6,11,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
Also Known As: 6alpha-Hydroxycortisol, 6-hydroxycortisol, A-Hydroxycortisol, 6?-Hydroxy Cortisol, A-Hydroxy Cortisol
| Molecular Formula | C21H30O6 |
|---|---|
| Molecular Weight | 378.20 g/mol |
| LogP | 0.3 |
| Topological Polar Surface Area | 115.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 378.20422 |
| Heavy Atoms | 27 |
| Complexity | 715.0 |
Chemical Identifiers
| CAS Number | 22561-27-9 |
|---|---|
| SMILES | C[C@]12CCC(=O)C=C1[C@H](C[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C)O)O |
| InChIKey | GNFTWPCIRXSCQF-HVIRSNARSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
6alpha-Hydroxycortisol (CAS 22561-27-9), with molecular formula C21H30O6 and molecular weight 378.20 g/mol. IUPAC: (6S,8S,9S,10R,11S,13S,14S,17R)-6,11,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one.
Chemical Property Profile of 6alpha-Hydroxycortisol
Property Insights of 6alpha-Hydroxycortisol
The XLogP value of 0.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 6alpha-Hydroxycortisol. The TPSA of 115.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 6alpha-Hydroxycortisol. Following Lipinski's Rule of Five, 6alpha-Hydroxycortisol has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6alpha-Hydroxycortisol?
The CAS number of 6alpha-Hydroxycortisol is 22561-27-9.
What is the molecular formula of 6alpha-Hydroxycortisol?
The molecular formula of 6alpha-Hydroxycortisol is C21H30O6.
What is the molecular weight of 6alpha-Hydroxycortisol?
The molecular weight of 6alpha-Hydroxycortisol is 378.20 g/mol.
Where can I buy 6alpha-Hydroxycortisol?
You can request a quote for 6alpha-Hydroxycortisol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6alpha-Hydroxycortisol?
Yes, KEHONG BIO provides custom synthesis services for 6alpha-Hydroxycortisol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.