6-chloro-N-(2,6-diisopropylphenyl)nicotinamide
TL;DR: 6-chloro-N-(2,6-diisopropylphenyl)nicotinamide (CAS 224817-05-4) is a chemical compound with molecular formula C18H21ClN2O and molecular weight 316.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-chloro-N-[2,6-di(propan-2-yl)phenyl]pyridine-3-carboxamide
Also Known As: 6-chloro-N-(2,6-diisopropylphenyl)nicotinamide, 6-chloro-N-[2,6-di(propan-2-yl)phenyl]pyridine-3-carboxamide, AO-854/43457719
| Molecular Formula | C18H21ClN2O |
|---|---|
| Molecular Weight | 316.13 g/mol |
| LogP | 5.2341 |
| Topological Polar Surface Area | 41.99 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 4 |
| Exact Mass | 316.13425 |
| Heavy Atoms | 22 |
| Complexity | 637.0374 |
Chemical Identifiers
| CAS Number | 224817-05-4 |
|---|---|
| SMILES | CC(C)C1=C(C(=CC=C1)C(C)C)NC(=O)C2=CN=C(C=C2)Cl |
Product Overview
6-chloro-N-(2,6-diisopropylphenyl)nicotinamide (CAS 224817-05-4), with molecular formula C18H21ClN2O and molecular weight 316.13 g/mol. IUPAC: 6-chloro-N-[2,6-di(propan-2-yl)phenyl]pyridine-3-carboxamide.
Chemical Property Profile of 6-chloro-N-(2,6-diisopropylphenyl)nicotinamide
Property Insights of 6-chloro-N-(2,6-diisopropylphenyl)nicotinamide
The XLogP value of 5.2341 indicates that 6-chloro-N-(2,6-diisopropylphenyl)nicotinamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.99 Ų, 6-chloro-N-(2,6-diisopropylphenyl)nicotinamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-chloro-N-(2,6-diisopropylphenyl)nicotinamide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-chloro-N-(2,6-diisopropylphenyl)nicotinamide?
The CAS number of 6-chloro-N-(2,6-diisopropylphenyl)nicotinamide is 224817-05-4.
What is the molecular formula of 6-chloro-N-(2,6-diisopropylphenyl)nicotinamide?
The molecular formula of 6-chloro-N-(2,6-diisopropylphenyl)nicotinamide is C18H21ClN2O.
What is the molecular weight of 6-chloro-N-(2,6-diisopropylphenyl)nicotinamide?
The molecular weight of 6-chloro-N-(2,6-diisopropylphenyl)nicotinamide is 316.13 g/mol.
Where can I buy 6-chloro-N-(2,6-diisopropylphenyl)nicotinamide?
You can request a quote for 6-chloro-N-(2,6-diisopropylphenyl)nicotinamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-chloro-N-(2,6-diisopropylphenyl)nicotinamide?
Yes, KEHONG BIO provides custom synthesis services for 6-chloro-N-(2,6-diisopropylphenyl)nicotinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.