N-(1,1-Bis-(4-fluorophenyl)-2,2,2-trifluoroethyl)-acetamide
TL;DR: N-(1,1-Bis-(4-fluorophenyl)-2,2,2-trifluoroethyl)-acetamide (CAS 2247-78-1) is a chemical compound with molecular formula C16H12F5NO and molecular weight 329.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[2,2,2-trifluoro-1,1-bis(4-fluorophenyl)ethyl]acetamide
Also Known As: N-[2,2,2-trifluoro-1,1-bis(4-fluorophenyl)ethyl]acetamide, N-(1,1-BIS-(4-FLUOROPHENYL)-2,2,2-TRIFLUOROETHYL)-ACETAMIDE, Acetamide, n-(2,2,2-trifluoro-1,1-bis(p-fluorophenyl)ethyl)-, N-(2,2,2-Trifluoro-1,1-bis(4-fluorophenyl)ethyl)acetamide, 654-311-7
| Molecular Formula | C16H12F5NO |
|---|---|
| Molecular Weight | 329.08 g/mol |
| LogP | 3.9 |
| Topological Polar Surface Area | 29.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 329.0839 |
| Heavy Atoms | 23 |
| Complexity | 387.0 |
Chemical Identifiers
| CAS Number | 2247-78-1 |
|---|---|
| SMILES | CC(=O)NC(C1=CC=C(C=C1)F)(C2=CC=C(C=C2)F)C(F)(F)F |
| InChIKey | LOOCAEGGZALYLF-UHFFFAOYSA-N |
Product Overview
N-(1,1-Bis-(4-fluorophenyl)-2,2,2-trifluoroethyl)-acetamide (CAS 2247-78-1), with molecular formula C16H12F5NO and molecular weight 329.08 g/mol. IUPAC: N-[2,2,2-trifluoro-1,1-bis(4-fluorophenyl)ethyl]acetamide.
Chemical Property Profile of N-(1,1-Bis-(4-fluorophenyl)-2,2,2-trifluoroethyl)-acetamide
Property Insights of N-(1,1-Bis-(4-fluorophenyl)-2,2,2-trifluoroethyl)-acetamide
The XLogP value of 3.9 indicates that N-(1,1-Bis-(4-fluorophenyl)-2,2,2-trifluoroethyl)-acetamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 29.1 Ų, N-(1,1-Bis-(4-fluorophenyl)-2,2,2-trifluoroethyl)-acetamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(1,1-Bis-(4-fluorophenyl)-2,2,2-trifluoroethyl)-acetamide has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(1,1-Bis-(4-fluorophenyl)-2,2,2-trifluoroethyl)-acetamide?
The CAS number of N-(1,1-Bis-(4-fluorophenyl)-2,2,2-trifluoroethyl)-acetamide is 2247-78-1.
What is the molecular formula of N-(1,1-Bis-(4-fluorophenyl)-2,2,2-trifluoroethyl)-acetamide?
The molecular formula of N-(1,1-Bis-(4-fluorophenyl)-2,2,2-trifluoroethyl)-acetamide is C16H12F5NO.
What is the molecular weight of N-(1,1-Bis-(4-fluorophenyl)-2,2,2-trifluoroethyl)-acetamide?
The molecular weight of N-(1,1-Bis-(4-fluorophenyl)-2,2,2-trifluoroethyl)-acetamide is 329.08 g/mol.
Where can I buy N-(1,1-Bis-(4-fluorophenyl)-2,2,2-trifluoroethyl)-acetamide?
You can request a quote for N-(1,1-Bis-(4-fluorophenyl)-2,2,2-trifluoroethyl)-acetamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(1,1-Bis-(4-fluorophenyl)-2,2,2-trifluoroethyl)-acetamide?
Yes, KEHONG BIO provides custom synthesis services for N-(1,1-Bis-(4-fluorophenyl)-2,2,2-trifluoroethyl)-acetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.